Evidence map›Paper›PMID 25897406›Full record

ArticleAMB Express2015

Sterilization of hydrogen peroxide resistant bacterial spores with stabilized chlorine dioxide.

Anthony Friedline, Malcolm Zachariah, Amy Middaugh, Matt Heiser, Neeraj Khanna, Parag Vaishampayan, Charles V Rice

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AMB Express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Chlorine Dioxide: Friend or Foe for Cell Biomolecules? A Chemical Approach.International journal of molecular sciences · 2022
    Review
  2. Article
  3. Inactivation of Spores and Vegetative Forms ofInternational journal of environmental research and public health · 2022
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anthony FriedlineDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, Oklahoma USA.
Malcolm ZachariahDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, Oklahoma USA.
Amy MiddaughDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, Oklahoma USA.
Matt HeiserBio-Cide International, Inc., Norman, Oklahoma USA.
Neeraj KhannaBio-Cide International, Inc., Norman, Oklahoma USA.
Parag VaishampayanJet Propulsion Laboratory, California Institute of Technology, Biotechnology and Planetary Protection Group, Pasadena, California USA.
Charles V RiceDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, Oklahoma USA.
University of Oklahoma · USJet Propulsion Laboratory · US

Funding

Metal Binding to the Bacterial Cell WallR01GM090064 · NIGMS · UNIVERSITY OF OKLAHOMA · PI RICE, CHARLES V · 2010 to 2014
$1.3M
NIGMS NIH HHS R01 GM090064
6 · The paper itself

Abstract

Bacillus pumilus SAFR-032 spores isolated from a clean room environment are known to exhibit enhanced resistance to peroxide, desiccation, UV radiation and chemical disinfection than other spore-forming bacteria. The survival of B. pumilus SAFR-032 spores to standard clean room sterilization practices requires development of more stringent disinfection agents. Here, we report the effects of a stabilized chlorine dioxide-based biocidal agent against spores of B. pumilus SAFR-032 and Bacillus subtilis ATCC 6051. Viability was determined via CFU measurement after exposure. Chlorine dioxide demonstrated efficacy towards sterilization of spores of B. pumilus SAFR-032 equivalent or better than exposure to hydrogen peroxide. These results indicate efficacy of chlorine dioxide delivered through a stabilized chlorine dioxide product as a means of sterilization of peroxide- and UV-resistant spores.

Indexed as

Bacillus pumilusBacillus subtilisChlorine dioxideSpore killingSpores

Identifiers

PMID25897406
PMCPMC4398677
OpenAlexW1988618541

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.