Evidence map›Paper›PMID 25897374›Full record

ArticleFacts, views & vision in ObGyn2015

A view on dendritic cell immunotherapy in ovarian cancer: how far have we come?

A Coosemans, T Baert, I Vergote

Abstract read
In one paragraph

Article in Facts, views & vision in ObGyn, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

A CoosemansDepartment of Oncology, KU Leuven, Herestraat 49, 3000 Leuven, Belgium. ; UZ Leuven, Gynaecology and Obstetrics, Herestraat 49, 3000 Leuven, Belgium.
T BaertDepartment of Oncology, KU Leuven, Herestraat 49, 3000 Leuven, Belgium. ; UZ Leuven, Gynaecology and Obstetrics, Herestraat 49, 3000 Leuven, Belgium.
I VergoteUZ Leuven, Gynaecology and Obstetrics, Herestraat 49, 3000 Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian cancer is the second most important pelvic gynaecologic malignancy and nowadays still kills 80% of patients. New treatment options are mandatory. Although it has been shown that ovarian cancer is an immunogenic tumor, the possibility of developing immunotherapy has been neglected for a long time. This article focuses on the importance of the immune system in the development and progression of cancer and the possibilities and problems of dendritic cell-based immunotherapy to influence the immune system.

Indexed as

cancerDCdendritic cellimmunotherapyOvarian cancertargeted therapy

Identifiers

PMID25897374
PMCPMC4402447

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.