ReviewWorld journal of diabetes2015
New-onset diabetes mellitus after kidney transplantation: Current status and future directions.
Review in World journal of diabetes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 4 of them syntheses that pooled it.
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Who cites it
52 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Prognostic impact of post-transplant diabetes mellitus in kidney allograft recipients: a meta-analysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025Pooled it
- Prevalence of new-onset diabetes mellitus after kidney transplantation: a systematic review and meta-analysis.Acta diabetologica · 2024Pooled it
- Association between Genetic Polymorphisms and Risk of Kidney Posttransplant Diabetes Mellitus: A Systematic Review and Meta-Analysis.International journal of clinical practice · 2022Pooled it
- A HuGE Review and Meta-Analyses of Genetic Associations in New Onset Diabetes after Kidney Transplantation.PloS one · 2016Pooled it
- Outcomes of renal transplantation in Africa: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2026Article
- The Association Between Variability in Tacrolimus Trough Levels and Posttransplant Diabetes Mellitus in Thai Kidney Transplant Patients.Transplantation direct · 2026Article
- Kidney transplantation in obese Black patients: Strategies to improve access and outcomes.World journal of nephrology · 2026Review
- Cost Impact of a Novel Pre-transplant Risk Assessment Tool for Early Acute Rejection in Kidney Transplant Patients.Journal of health economics and outcomes research · 2026Article
- Screening for Diabetes after Solid Organ Transplantation: A 10-Year Retrospective Study.EJIFCC · 2025Article
- Steroid Avoidance in Kidney Transplantation: From Vision to Velocity.Kidney international reports · 2025Article
- Trends and predictors of diabetes mellitus after living kidney transplantation: A retrospective study.World journal of diabetes · 2025Article
- Role of nutrition in diabetes mellitus and infections.World journal of clinical cases · 2025Article
- The incidence and risk factors of post-transplant diabetes mellitus in living donor kidney transplantation patients: a retrospective study.BMC nephrology · 2024Article
- Managing Post-Transplant Diabetes Mellitus after Kidney Transplantation: Challenges and Advances in Treatment.Pharmaceuticals (Basel, Switzerland) · 2024Review
- New-Onset Diabetes Mellitus after Kidney Transplantation.Journal of clinical medicine · 2024Review
- Prediction of diabetes mellitus after kidney transplantation using patient-specific induced pluripotent stem cells.Kidney research and clinical practice · 2024Article
- HbA1c changes in the first year post-kidney transplant and associated risk factors in a Saudi cohort.Therapeutic advances in endocrinology and metabolism · 2024Article
- Diabetic Kidney Disease in Post-Transplant Diabetes Mellitus: Causes, Treatment and Outcomes.Biomedicines · 2023Review
- Effect of histone deacetylase inhibitor (vorinostat) on new-onset diabetes induced by tacrolimus.Journal of Taibah University Medical Sciences · 2023Article
- Progress of new-onset diabetes after liver and kidney transplantation.Frontiers in endocrinology · 2023Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A diagnosis of new-onset diabetes after transplantation (NODAT) carries with it a threat to the renal allograft, as well as the same short- and long-term implications of type 2 diabetes seen in the general population. NODAT usually occurs early after transplantation, and is usually diagnosed according to general population guidelines. Non-modifiable risk factors for NODAT include advancing age, African American, Hispanic, or South Asian ethnicity, genetic background, a positive family history for diabetes mellitus, polycystic kidney disease, and previously diagnosed glucose intolerance. Modifiable risk factors for NODAT include obesity and the metabolic syndrome, hepatitis C virus and cytomegalovirus infection, corticosteroids, calcineurin inhibitor drugs (especially tacrolimus), and sirolimus. NODAT affects graft and patient survival, and increases the incidence of post-transplant cardiovascular disease. The incidence and impact of NODAT can be minimized through pre- and post-transplant screening to identify patients at higher risk, including by oral glucose tolerance tests, as well as multi-disciplinary care, lifestyle modification, and the use of modified immunosuppressive regimens coupled with glucose-lowering therapies including oral hypoglycemic agents and insulin. Since NODAT is a major cause of post-transplant morbidity and mortality, measures to reduce its incidence and impact have the potential to greatly improve overall transplant success.
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