ArticleNeuropsychiatric disease and treatment2015
"Recovery" from the diagnosis of autism - and then?
Article in Neuropsychiatric disease and treatment, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed.
- Chronic Physical Pain in Children With and Without Autism Spectrum Disorder in the United States: Findings from the 2016 - 2021 National Survey of Children's Health.Journal of autism and developmental disorders · 2026Article
- Clinical Features in Children With Loss of Autism Diagnosis and Persistent Autism: A Comparative Study.Journal of autism and developmental disorders · 2026Article
- Case report: Transient symptoms of autism spectrum disorder in a 2-year-old boy.Clinical case reports · 2023Article
- Blood Oxygen Level-Dependent Lag Patterns Differ Between Rest and Task Conditions, but Are Largely Typical in Autism.Brain connectivity · 2022Article
- Multimodal approaches to functional connectivity in autism spectrum disorders: An integrative perspective.Developmental neurobiology · 2018Review
- Speech and language profiles in 4- to 6-year-old children with early diagnosis of autism spectrum disorder without intellectual disability.Neuropsychiatric disease and treatment · 2018Article
- Effect of vitamin A supplementation on gut microbiota in children with autism spectrum disorders - a pilot study.BMC microbiology · 2017Article
- Children with borderline intellectual functioning and autism spectrum disorder: developmental trajectories from 4 to 11 years of age.Neuropsychiatric disease and treatment · 2017Article
- Genetic Evidence for Elevated Pathogenicity of Mitochondrial DNA Heteroplasmy in Autism Spectrum Disorder.PLoS genetics · 2016Article
- Preschool to School in Autism: Neuropsychiatric Problems 8 Years After Diagnosis at 3 Years of Age.Journal of autism and developmental disorders · 2016Article
- Children who screen positive for autism at 2.5 years and receive early intervention: a prospective naturalistic 2-year outcome study.Neuropsychiatric disease and treatment · 2016Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to follow up the 17 children, from a total group of 208 children with autism spectrum disorder (ASD), who "recovered from autism". They had been clinically diagnosed with ASD at or under the age of 4 years. For 2 years thereafter they received intervention based on applied behavior analysis. These 17 children were all of average or borderline intellectual functioning. On the 2-year follow-up assessment, they no longer met criteria for ASD.
methodsAt about 10 years of age they were targeted for a new follow-up. Parents were given a semistructured interview regarding the child's daily functioning, school situation, and need of support, and were interviewed using the Vineland Adaptive Behavior Scales (VABS) and the Autism - Tics, Attention-deficit/hyperactivity disorder (AD/HD), and other Comorbidities (A-TAC) telephone interview.
resultsThe vast majority of the children had moderate-to-severe problems with attention/activity regulation, speech and language, behavior, and/or social interaction. A majority of the children had declined in their VABS scores. Most of the 14 children whose parents were A-TAC-interviewed had problems within many behavioral A-TAC domains, and four (29%) had symptom levels corresponding to a clinical diagnosis of ASD, AD/HD, or both. Another seven children (50%) had pronounced subthreshold indicators of ASD, AD/HD, or both.
conclusionChildren diagnosed at 2-4 years of age as suffering from ASD and who, after appropriate intervention for 2 years, no longer met diagnostic criteria for the disorder, clearly needed to be followed up longer. About 3-4 years later, they still had major problems diagnosable under the umbrella term of ESSENCE (Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical Examinations). They continued to be in need of support, educationally, from a neurodevelopmental and a medical point of view. According to parent interview data, a substantial minority of these children again met diagnostic criteria for ASD.
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