ArticleNeuropsychiatric disease and treatment2015
Adherence and rehospitalizations in patients with schizophrenia: evidence from Japanese claims data.
Article in Neuropsychiatric disease and treatment, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Clinical, social, and economic burdens of schizophrenia in Japan: a targeted literature review.Schizophrenia (Heidelberg, Germany) · 2026Review
- Treatment continuation and factors associated with discontinuation with 3-month paliperidone palmitate in patients with schizophrenia: aFrontiers in psychiatry · 2026Article
- Article
- Impact of chronic potassium binder treatment on the clinical outcomes in patients with hyperkalemia: Results of a nationwide hospital-based cohort study.Frontiers in physiology · 2023Article
- Rehospitalization Rates Among Patients with Psychotic Disorders During Covid-19 Pandemic: Oral Versus Long-Acting Injectable Antipsychotics.Clinical neuropsychiatry · 2022Article
- Article
- The Use of the Japanese Public Financial Support Has Positive Impact on Persistence with Outpatient Treatments for Schizophrenia: Single-center Retrospective Cohort Study in Japan.Patient preference and adherence · 2021Article
- Time to Treatment Discontinuation in German Patients with Schizophrenia: Long-Acting Injectables versus Oral Antipsychotics.Clinical drug investigation · 2021Article
- The effect of non-adherence to antipsychotic treatment on rehospitalization in patients with psychotic disorders.Therapeutic advances in psychopharmacology · 2021Article
- Modeling the Choice Between Risperidone Long-Acting Injectable and Generic Risperidone from the Perspective of a Japanese Hospital.Neurology and therapy · 2019Article
- Persistence rates and medical costs of biological therapies for psoriasis treatment in Japan: a real-world data study using a claims database.BMC dermatology · 2018Article
- Cost of Depression in Japanese Patients with Rheumatoid Arthritis: Evidence from Administrative Data.Rheumatology and therapy · 2018Article
- Estimating Prevalence and Healthcare Utilization for Treatment-Resistant Depression in Japan: A Retrospective Claims Database Study.Drugs - real world outcomes · 2018Article
- Drug Utilization of Japanese Patients Diagnosed with Schizophrenia: An Administrative Database Analysis.Clinical drug investigation · 2017Article
- Productivity and deadweight losses due to relapses of schizophrenia in Japan.Neuropsychiatric disease and treatment · 2017Article
- Modeling the budget impact of long-acting injectable paliperidone palmitate in the treatment of schizophrenia in Japan.ClinicoEconomics and outcomes research : CEOR · 2015Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study is to analyze if there is a relationship between adherence to antipsychotic medication and rehospitalization for patients diagnosed with schizophrenia in Japan.
methodsBased on Japanese claims data, we constructed three patient groups based on their medication possession ratio (MPR). Controlling for potential confounders, a Cox proportional hazard model was employed to assess if medication adherence affects the risk of rehospitalization.
resultsPatients with good adherence (MPRs from 0.8-1.1) had the lowest rates of admission. Both poor adherence (MPRs <0.8) and overadherence (MPRs >1.1) were associated with a significant higher risk of rehospitalization with hazard ratios of 4.7 and 2.0, respectively.
conclusionThe results of this study support the notion that good adherence to antipsychotic medication reduces the risk of rehospitalization of schizophrenia patients. Appropriate measures should be taken to improve adherence of schizophrenia patients.
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