Evidence map›Paper›PMID 25897155›Full record

ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2015

Chimeric antigen receptor T cells for cancer immunotherapy.

Kevin J Curran, Renier J Brentjens

Abstract readComment
PubMed Publisher
In one paragraph

Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. CAR-T Cells: A Systematic Review and Mixed Methods Analysis of the Clinical Trial Landscape.Molecular therapy : the journal of the American Society of Gene Therapy · 2018
    Pooled it
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Review
  7. Advances in CAR-T cell therapy for malignant solid tumors.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2022
    Review
  8. Article
  9. Review
  10. Article
  11. Immunotherapeutic strategies for sarcoma: current perspectives.American journal of translational research · 2020
    Review
  12. Nanomaterial-Based Tumor Photothermal Immunotherapy.International journal of nanomedicine · 2020
    Review
  13. Article
  14. Local Phototherapy Synergizes with Immunoadjuvant for Treatment of Pancreatic Cancer through Induced Immunogenic Tumor Vaccine.Clinical cancer research : an official journal of the American Association for Cancer Research · 2018
    Article
  15. Building a Safer and Faster CAR: Seatbelts, Airbags, and CRISPR.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2018
    Review
  16. Review
  17. Article
  18. Flow Cytometry-based Assay for the Monitoring of NK Cell Functions.Journal of visualized experiments : JoVE · 2016
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Kevin J CurranMemorial Sloan Kettering Cancer Center, New York, NY.
Renier J BrentjensMemorial Sloan Kettering Cancer Center, New York, NY brentjer@mskcc.org.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bone NeoplasmsErb-b2 Receptor Tyrosine KinasesFemaleHumansImmunotherapyMaleSarcomaT-LymphocytesErb-b2 Receptor Tyrosine Kinases

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.