Evidence map›Paper›PMID 25897069›Full record

ArticleThe American journal of tropical medicine and hygiene2015

Collaborative health and enforcement operations on the quality of antimalarials and antibiotics in southeast Asia.

Yuk Lin Yong, Aline Plançon, Yen Hui Lau, Dana M Hostetler, Facundo M Fernández, Michael D Green, Sourisak Sounvoravong, Suon Nara, Mam Boravann, Thitikornkovit Dumrong and 5 more

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Response to antimicrobial resistance in South-East Asia Region.The Lancet regional health. Southeast Asia · 2023
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Triboelectric Nanogenerator (TENG) Mass Spectrometry of Falsified Antimalarials.Rapid communications in mass spectrometry : RCM · 2018
    Article
  10. Article
  11. A current perspective on antimicrobial resistance in Southeast Asia.The Journal of antimicrobial chemotherapy · 2017
    Article
  12. Article
  13. A Scan of CDC-Authored Articles on Legal Epidemiology, 2011-2015.Public health reports (Washington, D.C. : 1974) · 2016
    Article
  14. Review
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Yuk Lin Yong
Aline Plançon
Yen Hui Lau
Dana M Hostetler
Facundo M Fernández
Michael D Green
Sourisak Sounvoravong
Suon Nara
Mam Boravann
Thitikornkovit Dumrong
Nurjaya Bangsawan
Min Yong Low
Chin-Chin Lim
Ruth Lee Choo Ai
Paul N Newton

Funding

Wellcome Trust
6 · The paper itself

Abstract

Counterfeit (or falsified) and substandard medicines pose a major public health risk. We describe the findings of Operation Storm I and II conducted in 2008-2009 to combat counterfeit medicines through partnership between national customs, Drug Regulatory Agencies (DRAs), and police in Cambodia, Indonesia, Laos, Myanmar, Singapore, Thailand, and Vietnam. Samples were obtained from seizures and market surveillance by national DRAs. Laboratory analysis using spectroscopic and chromatographic techniques and examination of packaging were performed. Ninety-three suspect antibiotics and 95 antimalarial samples were collected. Of the 93 antibiotics, 29 (31%) had % active pharmaceutical ingredient content (%API) < 85% or > 115% (including one counterfeit). Of the 95 antimalarials, 30 (32%) had %API < 85 > 115% API (including one counterfeit). A significant minority of samples, antimalarials (13%) and antibiotics (15%), were collected in plastic bags with minimal or no labeling. Of 20 ampicillin samples, 13 (65%) contained < 85% API (with one counterfeit containing additional amoxicillin). Of 34 oral artesunate samples, 7 (21%) contained %API out of the 85-115% range. Coordinated and synergistic partnership adopted by the participating countries, International Criminal Police Organization (INTERPOL), World Health Organization (WHO), and laboratories facilitated a platform for discussions and intelligence sharing, helping to improve each participating country's capacity to combat poor-quality medicines.

Indexed as

Counterfeit DrugsInternational CooperationAnti-Bacterial AgentsAntimalarialsAsia, SoutheasternDrug PackagingLegislation, DrugAnti-Bacterial AgentsAntimalarialsCounterfeit Drugs

Identifiers

PMID25897069
PMCPMC4455084
OpenAlexW2126533828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.