Evidence map›Paper›PMID 25896674›Full record

ArticleBMC musculoskeletal disorders2015

Prevalence and risk factors for patient-reported joint pain among patients with HIV/hepatitis C coinfection, hepatitis C monoinfection, and HIV monoinfection.

Alexis Ogdie, Wyki Gina Pang, Kimberly A Forde, Bhangle D Samir, Lakeisha Mulugeta, Kyong-Mi Chang, David E Kaplan, Valerianna K Amorosa, Jay R Kostman, Rajender K Reddy and 2 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC musculoskeletal disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Observational
  2. Review
  3. Observational
  4. Article
  5. Cigarette Smoking Behaviors and Beliefs in Persons Living With Hepatitis C.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alexis OgdieDivision of Rheumatology, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Penn Tower Room 1407, 1 Convention Ave, Philadelphia, PA 19104, USA. Alexis.ogdie@uphs.upenn.edu.
Wyki Gina PangMaine Medical Center, Tufts University School of Medicine, Portland, ME, USA.
Kimberly A FordeDepartment of Medicine, Division of Gastroenterology, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. kimberly.forde@uphs.upenn.edu.
Bhangle D SamirSeacoast Arthritis and Osteoporosis Center, 10 Members Way, Suite 403, Dover, NH 03820, USA. samirbhangle@hotmail.com.
Lakeisha MulugetaPerelman School of Medicine, the University of Pennsylvania, Philadelphia, PA, USA. Lakeisha.mulugeta@gmail.com.
Kyong-Mi ChangDivision of Gastroenterology, Philadelphia VA Medical Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. kmchang@mail.med.upenn.edu.
David E KaplanDivision of Gastroenterology, Philadelphia VA Medical Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. dakaplan@mail.med.upenn.edu.
Valerianna K AmorosaDivision of Infectious Diseases, Philadelphia VA Medical Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. Valerianna.amorosa@uphs.upenn.edu.
Jay R KostmanDivision of Infectious Diseases, Philadelphia VA Medical Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. Jay.kostman@uphs.upenn.edu.
Rajender K ReddyDivision of Gastroenterology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA. Rajendar.reddy@uphs.upenn.edu.
Ralph H SchumacherDivision of Rheumatology, Philadelphia VA Medical Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. schumacr@mail.med.upenn.edu.
Vincent Lo ReDepartment of Medicine, Division of Infectious Diseases, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. vincentl@mail.med.upenn.edu.

Funding

Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ROBERT GROSS · 1999 to 2026
$78.6M
Identification of Early Psoriatic ArthritisK23AR063764 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI OGDIE, ALEXIS R. · 2013 to 2017
$751k
Risk factors and prediction of liver disease in HIV/HCVK01AI070001 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI LO RE, VINCENT · 2007 to 2011
$665k
Mechanisms of Cellular Immune Dysfunction in Patients with Hepatitis C Virus andI01BX000649 · VA · PHILADELPHIA VA MEDICAL CENTER · PI CHANG, KYONG-MI · 2009 to 2013
–
NIAID NIH HHS K01 AI 070001NIAID NIH HHS K01 AI070001NIAID NIH HHS P30 AI045008NIAMS NIH HHS K23 AR063764
6 · The paper itself

Abstract

backgroundTo determine the prevalence of patient-reported joint pain among patients with human immunodeficiency virus (HIV)/chronic hepatitis C virus (HCV) coinfection, chronic HCV monoinfection, and HIV monoinfection followed in hepatology and infectious disease outpatient practices.

methodsStandardized interviews were performed among 79 HIV/HCV-coinfected, 93 HCV-monoinfected, and 30 HIV-monoinfected patients in a cross-sectional study within hepatology and infectious disease clinics at three centers. The Multi-Dimensional Health Assessment Questionnaire was used to ascertain joint pain and associated symptoms. Information on potential risk factors for joint pain was obtained during the interview and by chart review. Logistic regression was used to determine adjusted odds ratios (aORs) with 95% confidence intervals (CIs) of joint pain associated with risk factors of interest among chronic HCV-infected and HIV-infected patients.

resultsJoint pain was more commonly reported in HCV-monoinfected than HIV/HCV-coinfected (71% versus 56%; p = 0.038) and HIV-monoinfected (71% versus 50%; p = 0.035) patients. A previous diagnosis of arthritis and current smoking were risk factors for joint pain among HCV-infected patients (arthritis: aOR, 4.25; 95% CI, 1.84-9.81; smoking: aOR, 5.02; 95% CI, 2.15-11.74) and HIV-infected (arthritis: aOR, 5.36; 95% CI, 2.01-14.25; smoking: aOR, 6.07; 95% CI, 2.30-16.00) patients.

conclusionPatient-reported joint pain was prevalent among all three groups, but more common among chronic HCV-monoinfected than either HIV/HCV-coinfected or HIV-monoinfected patients. A prior diagnosis of arthritis and current smoking were risk factors for patient-reported joint pain among both HCV-infected and HIV-infected patients.

Indexed as

Interviews as TopicAdultArthralgiaArthritisComorbidityCross-Sectional StudiesFemaleHepacivirusHepatitis C, ChronicHIVHIV InfectionsHumansLogistic ModelsMaleMiddle AgedPrevalence

Identifiers

PMID25896674
PMCPMC4404567

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.