ArticleClinical research in cardiology : official journal of the German Cardiac Society2015
The impact of transcatheter aortic valve implantation on quality of life: results from the German transcatheter aortic valve interventions registry.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- The effects of frailty, mental health, and cardiac function on quality of life in patients undergoing transcatheter aortic valve replacement.Scientific reports · 2025Article
- Osteosarcopenia in older adults undergoing transcatheter aortic valve replacement: A narrative review of mortality and frailty implications.World journal of cardiology · 2025Review
- Review
- Immediate reduction in left ventricular ejection time following TAVI is associated with improved quality of life.Frontiers in cardiovascular medicine · 2022Article
- A Novel Method to Predict Mortality and Length of Stay after Transfemoral Transcatheter Aortic Valve Implantation.Medicina (Kaunas, Lithuania) · 2021Article
- Impact of frailty on health-related quality of life 1 year after transcatheter aortic valve implantation.Age and ageing · 2020Observational
- Life beyond 5 Years after TAVI: Patients' Perceived Health Status and Long-Term Outcome after Transcatheter Aortic Valve Implantation.Journal of interventional cardiology · 2019Article
- Health-related quality of life following transcatheter aortic valve implantation using transaortic, transfemoral approaches and surgical aortic valve replacement-a single-center study.Journal of geriatric cardiology : JGC · 2018Article
- Long-term follow-up of quality of life in high-risk patients undergoing transcatheter aortic valve implantation for symptomatic aortic valve stenosis.Journal of geriatric cardiology : JGC · 2018Article
- Frailty and Exercise Training: How to Provide Best Care after Cardiac Surgery or Intervention for Elder Patients with Valvular Heart Disease.BioMed research international · 2018Review
- Prevalence, predictors, and prognostic implications of residual impairment of functional capacity after transcatheter aortic valve implantation.Clinical research in cardiology : official journal of the German Cardiac Society · 2017Article
- Thrombosis of TAVI prosthesis-cause for concern or innocent bystander? A comment and review of currently available data.Clinical research in cardiology : official journal of the German Cardiac Society · 2017Article
- Prognostic value of body mass index and body surface area on clinical outcomes after transcatheter aortic valve implantation.Clinical research in cardiology : official journal of the German Cardiac Society · 2016Observational
- Improvements in quality of life in septuagenarians versus octogenarians undergoing trans-catheter aortic valve replacement.Journal of geriatric cardiology : JGC · 2016Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTranscatheter aortic valve implantation (TAVI) has proven a survival benefit in patients with severe symptomatic aortic stenosis (AS). Recently published data from the German TAVI registry reported a 1-year mortality rate of 19.9 %. However, there are limited data for the effect of TAVI on quality of life (QoL), especially in real life settings.
methodsThe German TAVI registry was launched to evaluate safety, effectiveness and QoL of TAVI in daily clinical routine. We analyzed health-related QoL, using the EQ-5D questionnaire.
resultsQuality-of-life data were eligible for 460 patients who survived 12 months after TAVI (82.5 ± 6.0 years; 32.2 % men). At baseline, QoL (EQ-5D-index: 0.63 ± 0.26) was markedly depressed, but significantly improved 30 days and 12 months (0.67 ± 0.24; 0.70 ± 0.24; p < 0.0001) after TAVI procedure. In addition, the visual analogue health scale, recording the patient's self-rated health, significantly (p < 0.0001) increased from 42.0 ± 15.9 % at baseline to 57.0 ± 17.2 % (30 days) and 57.7 ± 19.6 % (12 months). A lower EQ-5D-index at baseline, a percutaneous transfemoral/transaxillar TAVI procedure, and indications other than frailty for TAVI were determinants for an improved QoL 1 year after TAVI.
conclusionsAmong patients with AS, TAVI resulted in meaningful improvements in QoL. This benefit was present shortly after TAVI and maintained for at least 1 year. Different gains in QoL regarding patient-subgroups and determinants for improved QoL could give further impetus for patient selection.
Indexed as
Identifiers
25896479What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.