ArticleScientific reports2015
Deciphering the venomic transcriptome of killer-wasp Vespa velutina.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 58 citations in OpenAlex.
- Article
- [Insect venom allergies-What will change in times of global change?]Dermatologie (Heidelberg, Germany) · 2024Review
- Article
- Modeling abundance and risk impact of Vespa velutina nigrithorax (Hymenoptera: Vespidae) in Korea: application of a species abundance model.Scientific reports · 2023Article
- Proteomics ofToxins · 2023Article
- Venom profile of the European carpenter beeToxicon: X · 2022Article
- Bioactive Peptides and Proteins from Wasp Venoms.Biomolecules · 2022Review
- Stings on wings: Proteotranscriptomic and biochemical profiling of the lesser banded hornet (Frontiers in molecular biosciences · 2022Article
- Hornets and Honey Bees: A Coevolutionary Arms Race between Ancient Adaptations and New Invasive Threats.Insects · 2021Review
- Anti-Inflammatory Effect of Wasp Venom in BV-2 Microglial Cells in Comparison with Bee Venom.Insects · 2021Article
- Multiple transcriptome mining coupled with tissue specific molecular cloning and mass spectrometry provide insights into agatoxin-like peptide conservation in decapod crustaceans.General and comparative endocrinology · 2020Article
- Transcriptome profiling of venom gland from wasp species: de novo assembly, functional annotation, and discovery of molecular markers.BMC genomics · 2020Article
- Article
- Notes on the Nest Architecture and Colony Composition in Winter of the Yellow-Legged Asian Hornet,Insects · 2019Article
- Transcriptomic analysis of grain filling in rice inferior grains under moderate soil drying.Journal of experimental botany · 2019Article
- Biochemical characterization of a phospholipase AThe journal of venomous animals and toxins including tropical diseases · 2018Article
- Venomics of Remipede Crustaceans Reveals Novel Peptide Diversity and Illuminates the Venom's Biological Role.Toxins · 2017Article
- Differential Properties of Venom Peptides and Proteins in Solitary vs. Social Hunting Wasps.Toxins · 2016Review
- Dual Identification and Analysis of Differentially Expressed Transcripts of Porcine PK-15 Cells and Toxoplasma gondii during in vitro Infection.Frontiers in microbiology · 2016Article
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wasp stings have been arising to be a severe public health problem in China in recent years. However, molecular information about lethal or toxic factors in wasp venom is extremely lacking. In this study, we used two pyrosequencing platforms to analyze the transcriptome of Vespa velutina, the most common wasp species native in China. Besides the substantial amount of transcripts encoding for allergens usually regarded as the major lethal factor of wasp sting, a greater abundance of hemostasis-impairing toxins and neurotoxins in the venom of V. velutina were identified, implying that toxic reactions and allergic effects are envenoming strategy for the dangerous outcomes. The pattern of differentially expressed genes before and after venom extraction clearly indicates that the manifestation of V. velutina stings depends on subtle regulations in the metabolic pathway required for toxin recruitment. This comparative analysis offers timely clues for developing clinical treatments for wasp envenoming in China and around the world.
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