ArticleParasites & vectors2015
Cross sectional study of prevalence, genetic diversity and zoonotic potential of Cryptosporidium parvum cycling in New Zealand dairy farms.
Article in Parasites & vectors, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cryptosporidium infections in terrestrial ungulates with focus on livestock: a systematic review and meta-analysis.Parasites & vectors · 2019Pooled it
- Prevalence and molecular characterization ofFrontiers in veterinary science · 2025Article
- Article
- First Molecular Genotyping ofArchives of Razi Institute · 2022Article
- Small ruminants and zoonotic cryptosporidiosis.Parasitology research · 2021Review
- First Molecular Characterization ofPathogens (Basel, Switzerland) · 2021Article
- Prevalence and distribution pattern of Cryptosporidium spp. among pre-weaned diarrheic calves in the Republic of Korea.PloS one · 2021Article
- Association of Common Zoonotic Pathogens With Concentrated Animal Feeding Operations.Frontiers in microbiology · 2021Review
- In Silico Identification and Functional Characterization of Conserved miRNAs in the Genome ofBioinformatics and biology insights · 2021Article
- Species and genotypes causing human cryptosporidiosis in New Zealand.Parasitology research · 2020Article
- Dairy Calves in Uruguay Are Reservoirs of Zoonotic Subtypes ofFrontiers in veterinary science · 2020Article
- Molecular characterization of Cryptosporidium isolates from diarrheal dairy calves in France.Veterinary parasitology, regional studies and reports · 2019Article
- Local and global genetic diversity of protozoan parasites: Spatial distribution of Cryptosporidium and Giardia genotypes.PLoS neglected tropical diseases · 2017Observational
- Cryptosporidiosis Risk in New Zealand Children Under 5 Years Old is Greatest in Areas with High Dairy Cattle Densities.EcoHealth · 2016Article
- Spatial Modelling Tools to Integrate Public Health and Environmental Science, Illustrated with Infectious Cryptosporidiosis.International journal of environmental research and public health · 2016Review
- Revisiting the global problem of cryptosporidiosis and recommendations.Tropical parasitologyArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe estimation of the prevalence and zoonotic potential of Cryptosporidium parvum cycling in bovine populations requires the use of genotyping, as several morphologically similar non-parvum genetic variants of unproven clinical and public health impact are found in cattle. However, robust C. parvum prevalence estimates in cattle are lacking and comparative data of bovine and human isolates collected from the same regions are scarce. Thus, the relative contribution of the C. parvum oocysts released by farmed animals to animal and human cryptosporidiosis burden is, in general, poorly understood.
methodsThe New Zealand farm-level C. parvum prevalence was estimated using a cross-sectional sample of 1283 faecal specimens collected from newborn calves on 97 dairy farms. Faeces were analysed by immunofluorescence and the Cryptosporidium parasites were genetically identified. Finally, bovine C. parvum were genetically compared with historical human clinical isolates using a bilocus subtyping scheme.
resultsImmunofluoresence-positive faeces were found in 63/97 (65%) farms. C. parvum was identified in 49 (50.5%) farms, C. bovis in 6 (6.1%) farms, and on 8 (8.2%) farms the species could not be identified. The dominant C. parvum genetic variants were geographically widespread and found in both host populations, but several variants were found in humans only.
conclusionsPhenotypic tests offered by New Zealand veterinary diagnostic laboratories for the diagnosis of C. parvum may have moderate to high positive predictive values for this species. The genetic similarities observed between the human and bovine parasites support a model considering calves as significant amplifiers of zoonotic C. parvum in New Zealand. However, data suggest that transmission routes not associated with dairy cattle should also be taken into account in future source-attribution studies of human cryptosporidiosis.
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