Evidence map›Paper›PMID 25896340›Full record

ArticleBMC pulmonary medicine2015

BMI, waist circumference at 8 and 12 years of age and FVC and FEV1 at 12 years of age; the PIAMA birth cohort study.

Marga B Bekkers, Alet H Wijga, Ulrike Gehring, Gerard H Koppelman, Johan C de Jongste, Henriette A Smit, Bert Brunekreef

Open access · goldAbstract read
In one paragraph

Article in BMC pulmonary medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

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  3. Prevalence, Medicaid use and mortality risk of low FEVBMJ open respiratory research · 2024
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  10. Is obesity related to the lung function of non-asthmatic children?World journal of clinical pediatrics · 2018
    Review
  11. Observational
  12. Article
  13. The effect of scoliosis surgery on pulmonary function in spinal muscular atrophy type II patients.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2017
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Marga B BekkersInstitute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, The Netherlands. m.bekkers@hotmail.com.
Alet H WijgaCentre for Nutrition, Prevention and Health Services, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands. alet.wijga@rivm.nl.
Ulrike GehringInstitute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, The Netherlands. u.gehring@uu.nl.
Gerard H KoppelmanDepartment of Pulmonology and Pediatric Allergology, GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. g.h.koppelman@umcg.nl.
Johan C de JongsteDepartment of Pediatrics, Erasmus University Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands. j.c.dejongste@erasmusmc.nl.
Henriette A SmitJulius Centre for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands. H.A.Smit@umcutrecht.nl.
Bert BrunekreefInstitute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, The Netherlands. b.brunekreef@uu.nl.
Utrecht University · NLErasmus MC · NLNational Institute for Public Health and the Environment · NLUniversity Medical Center Groningen · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn adults, overweight is associated with reduced lung function, in children evidence on this association is conflicting. We examined the association of body mass index (BMI) and waist circumference (WC) at age 12, and of persistently (at ages 8 and 12 years) high BMI and large WC, with forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV1) at age 12.

methodsHeight, weight, WC and FVC and FEV1 were measured during a medical examination in 1288 12-year-olds participating in the PIAMA birth cohort study. 1090 children also had BMI and WC measured at age 8. The associations between BMI and WC and FVC, FEV1, and FEV1/FVC ratio were studied using local and linear regression analyses, separately for girls and boys. The regression models were adjusted for age, height, and pubertal development and maternal educational level.

resultsHigh BMI and large WC (sd-score >90th percentile) were associated with higher FVC; in girls these associations were statistically significant (4.6% (95% CI: 1.5, 7.9) and 3.6% (95% CI: 0.6, 6.8) respectively in adjusted models). Similar associations were observed for persistently high BMI or large WC: girls with a high BMI or large WC at both 8 and 12 years had statistically significantly higher FVC at age 12 years (BMI: 4.9% (95% CI 0.9, 9.1), WC: 5.0% (95% CI 0.7, 9.6)) than girls with normal BMI or WC at both ages. No statistically significant associations were observed between (persistently) high BMI or large WC and FEV1. The FEV1/FVC ratio was statistically significantly lower in children with a high BMI or large WC than in children with a normal BMI or WC. Girls and boys with a persistently high BMI or large WC status had statistically significantly lower FEV1/FVC ratios.

conclusionAt 12 years of age, a persistently high BMI or large WC is not yet associated with lower FVC and FEV1, suggesting that this association, that is commonly observed in adults, develops at a later age.

Indexed as

Body Mass IndexChildCross-Sectional StudiesDenmarkFemaleForced Expiratory VolumeHumansLungMaleOverweightRespiratory Function TestsRisk FactorsVital CapacityWaist Circumference

Identifiers

PMID25896340
PMCPMC4409985
OpenAlexW2103695822

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.