Evidence map›Paper›PMID 25896194›Full record

ArticleAmerican journal of preventive medicine2015

HIV Infection Status as a Predictor of Hepatitis C Virus RNA Testing in Primary Care.

Anthony K Yartel, Rebecca L Morgan, David B Rein, Kimberly Ann Brown, Natalie B Kil, Omar I Massoud, Michael B Fallon, Bryce D Smith

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in American journal of preventive medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Anthony K YartelCDC Foundation, Atlanta, Georgia. Electronic address: jqi0@cdc.gov.
Rebecca L MorganDivision of Viral Hepatitis, CDC, Atlanta, Georgia.
David B ReinPublic Health Department, NORC at the University of Chicago, Atlanta, Georgia.
Kimberly Ann BrownDepartment of Medicine, Henry Ford Hospital, Detroit, Michigan.
Natalie B KilDepartment of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
Omar I MassoudDepartment of Medicine, University of Alabama at Birmingham (Massoud), Birmingham, Alabama.
Michael B FallonDepartment of Internal Medicine, the University of Texas Medical School at Houston (Fallon), Houston, Texas.
Bryce D SmithDivision of Viral Hepatitis, CDC, Atlanta, Georgia.
CDC Foundation · USHenry Ford Hospital · USIcahn School of Medicine at Mount Sinai · USUniversity of Alabama at Birmingham · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

introductionReceipt of hepatitis C virus (HCV) RNA testing following a positive HCV antibody (anti-HCV+) test result to establish current infection is a quality indicator for HCV-related care. This study examines HIV infection status as a predictor of HCV RNA test receipt after an anti-HCV+ result in the primary care setting.

methodsElectronic medical records of anti-HCV+ patients from a multisite retrospective study of patients aged ≥18 years who utilized one or more primary care outpatient services during 2005-2010 were analyzed in 2014. A multivariable logistic regression model examined the independent relationships between patient characteristics and receipt of HCV RNA testing.

resultsAmong 1,115 anti-HCV+ patients, 133 (11.9%) were also HIV-positive. Of these, 77.4% (n=103) underwent HCV RNA testing to determine current infection status. By contrast, 66.7% (n=654/980) of anti-HCV+ patients who were HIV-negative received HCV RNA testing. Following multivariable adjustment, the odds of receiving HCV RNA testing were higher among anti-HCV+ patients who were also HIV-positive (AOR=1.9, 95% CI=1.2, 3.0), compared with their HIV-negative counterparts. Elevated alanine aminotransferase level was also associated with receipt of HCV RNA testing (AOR=1.9, 95% CI=1.4, 2.4). Black race was associated with decreased odds of receiving HCV RNA testing (AOR=0.7, 95% CI=0.5, 1.0).

conclusionsHIV infection status is independently associated with the likelihood of receiving HCV RNA testing following an anti-HCV+ result. One quarter of anti-HCV+ patients who were also HIV-positive and one third of their HIV-negative counterparts, respectively, did not receive testing to establish active HCV infection, which is imperative for appropriate care and treatment.

Indexed as

FemaleHepatitis CHepatitis C AntibodiesHIV InfectionsHumansLogistic ModelsMaleMiddle AgedPrimary Health CareQuality Indicators, Health CareQuality of Health CareRetrospective StudiesRNA, ViralHepatitis C AntibodiesRNA, Viral

Identifiers

PMID25896194
PMCPMC4556132
OpenAlexW2016999548

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.