Evidence map›Paper›PMID 25895940›Full record

ReviewNature reviews. Microbiology2015

Living in the matrix: assembly and control of Vibrio cholerae biofilms.

Jennifer K Teschler, David Zamorano-Sánchez, Andrew S Utada, Christopher J A Warner, Gerard C L Wong, Roger G Linington, Fitnat H Yildiz

Abstract readReview
In one paragraph

Review in Nature reviews. Microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 216 papers.

0numbers the graph read from it
0cells of the map it votes in
216citing papers in PubMed
30.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

216 citing papers in PubMed, 413 citations in OpenAlex.

  1. Review
  2. Article
  3. A biofilm-derived peptide as an underwater adhesive.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Structural basis of multimodal adsorption and infection initiation bybioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Article
  8. Light-activated cAMP signaling controls sodium-driven motility inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  9. Article
  10. Article
  11. Antibacterial and Antibiofilm Activities of Bluestem (International journal of microbiology · 2026
    Article
  12. The BaeS/BaeR two-component system enhancesFrontiers in cellular and infection microbiology · 2026
    Article
  13. Nitric oxide promotes rapid development of motility to accelerate biofilm dispersal inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  14. bioRxiv : the preprint server for biology · 2025
    Article
  15. Article
  16. Article
  17. Review
  18. Dissecting the physics of bacterial biofilms with agent-based simulations.Current opinion in solid state & materials science · 2025
    Article
  19. Article
  20. Article

156 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jennifer K TeschlerDepartment of Microbiology and Environmental Toxicology, University of California, Santa Cruz, California 95064, USA.
David Zamorano-SánchezDepartment of Microbiology and Environmental Toxicology, University of California, Santa Cruz, California 95064, USA.
Andrew S UtadaBioengineering Department, Chemistry and Biochemistry Department, California NanoSystems Institute, University of California, Los Angeles, California 90095, USA.
Christopher J A WarnerDepartment of Chemistry and Biochemistry, University of California, Santa Cruz, California 95064, USA.
Gerard C L WongBioengineering Department, Chemistry and Biochemistry Department, California NanoSystems Institute, University of California, Los Angeles, California 90095, USA.
Roger G LiningtonDepartment of Chemistry and Biochemistry, University of California, Santa Cruz, California 95064, USA.
Fitnat H YildizDepartment of Microbiology and Environmental Toxicology, University of California, Santa Cruz, California 95064, USA.
University of California, Santa Cruz · US

Funding

Vibrio cholerae c-diGMP signaling: Motile to biofilm transition and transmissionR01AI102584 · NIAID · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI YILDIZ, HAVVA FITNAT · 2013 to 2023
$6.5M
Vibrio cholerae biofilms: structure, function, regulation and role in infectionR01AI114261 · NIAID · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI YILDIZ, HAVVA FITNAT · 2014 to 2024
$5.0M
Smooth to Rugose phase variation in Vibrio choleraeR01AI055987 · NIAID · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI YILDIZ, HAVVA FITNAT · 2003 to 2019
$4.4M
Vibrio cholerae c-diGMP signaling: motile to biofilm transition and transmissionR56AI102584 · NIAID · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI YILDIZ, HAVVA FITNAT · 2012 to 2012
$608k
Smooth to Rugose phase variation in Vibrio choleraeR56AI055987 · NIAID · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI YILDIZ, HAVVA FITNAT · 2008 to 2008
$356k
NIAID NIH HHS AI055987NIAID NIH HHS AI102584NIAID NIH HHS AI114261NIAID NIH HHS R01 AI055987NIAID NIH HHS R01 AI102584NIAID NIH HHS R01 AI114261NIAID NIH HHS R56 AI055987NIAID NIH HHS R56 AI102584
6 · The paper itself

Abstract

Nearly all bacteria form biofilms as a strategy for survival and persistence. Biofilms are associated with biotic and abiotic surfaces and are composed of aggregates of cells that are encased by a self-produced or acquired extracellular matrix. Vibrio cholerae has been studied as a model organism for understanding biofilm formation in environmental pathogens, as it spends much of its life cycle outside of the human host in the aquatic environment. Given the important role of biofilm formation in the V. cholerae life cycle, the molecular mechanisms underlying this process and the signals that trigger biofilm assembly or dispersal have been areas of intense investigation over the past 20 years. In this Review, we discuss V. cholerae surface attachment, various matrix components and the regulatory networks controlling biofilm formation.

Indexed as

Bacterial AdhesionBiofilmsEnvironmental MicrobiologySignal TransductionVibrio cholerae

Identifiers

PMID25895940
PMCPMC4437738
OpenAlexW2033701627

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.