Evidence map›Paper›PMID 25894962›Full record

SynthesisInternational urology and nephrology2015

The impact of female gender on bladder cancer-specific death risk after radical cystectomy: a meta-analysis of 27,912 patients.

Shenghua Liu, Tian Yang, Rong Na, Mengbo Hu, Limin Zhang, You Fu, Haowen Jiang, Qiang Ding

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in International urology and nephrology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Outcomes with atezolizumab in metastatic urothelial cancer: real-world data from a single institution.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Bladder Cancer Survivorship.Current urology reports · 2018
    Review
  16. Edaravone Improves Septic Cardiac Function by Inducing an HIF-1Oxidative medicine and cellular longevity · 2018
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shenghua LiuFudan Institute of Urology, Huashan Hospital, Fudan University, Shanghai, China.
Tian Yang
Rong Na
Mengbo Hu
Limin Zhang
You Fu
Haowen Jiang
Qiang Ding

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo perform a first meta-analysis on the association between female gender and cancer-specific death risk after radical cystectomy. MATERIALS AND

methodsA comprehensive literature search of the MEDLINE and EMBASE databases was conducted for relevant studies published till November 11, 2014. The meta-analysis was performed by estimating the hazard ratios (HRs) and confidence intervals (CIs) through a random-effect approach.

resultsA total of 17 studies were included in the meta-analysis with a total population of 27,912 patients. Female gender was associated with a worse survival outcome (pooled HR 1.20; 95 % CI 1.09-1.32) compared with male gender after radical cystectomy. Subgroup analysis found the correlation was significant in North American and European studies (HR 1.17, 95 % CI 1.02-1.32 and HR 1.34, 95 % CI 1.19-1.51, respectively) and studies from larger size of samples (HR 1.24, 95 % CI 1.11-1.38). We also found studies adjusted for the key elements (T stage, N stage and grade) obtained positive correlation (HR 1.21, 95 % CI 1.09-1.35).

conclusionsFemale demonstrated worse survival outcomes than male after radical cystectomy for bladder cancer. The adoption of more intense cares for female patients was suggested after radical cystectomy.

Indexed as

CystectomyFemaleHumansMaleRisk AssessmentSex DistributionSex FactorsUrinary Bladder Neoplasms

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.