ArticleSensors (Basel, Switzerland)2015
Stand-off biodetection with free-space coupled asymmetric microsphere cavities.
Article in Sensors (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Optical whispering gallery mode resonators: analysing thermo-optic tuning in a silicon sphere.Journal of the Royal Society of New Zealand · 2025Article
- Liquid Droplet Microresonators.Sensors (Basel, Switzerland) · 2019Review
- Whispering-Gallery Mode Resonators for Detecting Cancer.Sensors (Basel, Switzerland) · 2017Review
- Fundamental limits in high-Q droplet microresonators.Scientific reports · 2017Article
- Biosensing by WGM Microspherical Resonators.Sensors (Basel, Switzerland) · 2016Review
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Asymmetric microsphere resonant cavities (ARCs) allow for free-space coupling to high quality (Q) whispering gallery modes (WGMs) while exhibiting highly directional light emission, enabling WGM resonance measurements in the far-field. These remarkable characteristics make "stand-off" biodetection in which no coupling device is required in near-field contact with the resonator possible. Here we show asymmetric microsphere resonators fabricated from optical fibers which support dynamical tunneling to excite high-Q WGMs, and demonstrate free-space coupling to modes in an aqueous environment. We characterize the directional emission by fluorescence imaging, demonstrate coupled mode effects due to free space coupling by dynamical tunneling, and detect adsorption kinetics of a protein in aqueous solution. Based on our approach, new, more robust WGM biodetection schemes involving microfluidics and in-vivo measurements can be designed.
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Registered trials
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