SynthesisMaternal & child nutrition2016
Systematic review of randomised controlled trials of interventions that aim to reduce the risk, either directly or indirectly, of overweight and obesity in infancy and early childhood.
Synthesis in Maternal & child nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 118 papers, 17 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
"Improved Mother Infant Feeding Interaction (MI-FI) at 12 Months With Very Early Parent
Cluster Randomised Controlled Feasibility Study of HENRY; a Community Based Intervention Aimed at Reducing School Entry Obesity Rates
INFANT HEALTH- Supporting Infants' Mental Health and Healthy Weight Development Through Community Health Nurses' Promoting Sensitive Parenting
Who cites it
118 citing papers in PubMed, 17 syntheses or guidelines pooled it.
- Interventions to Reduce Screen Time in Preschool-Aged Children: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Pooled it
- Public health interventions for the prevention and management of overweight and obesity in children and adolescents: a rapid review.Frontiers in public health · 2026Pooled it
- Nutrition interventions in the first 1000 days and long-term health outcomes: a systematic review.Pediatric research · 2025Pooled it
- Parental engagement with complementary feeding information in the United Kingdom: A qualitative evidence synthesis.Maternal & child nutrition · 2023Pooled it
- The effectiveness of interventions during the first 1,000 days to improve energy balance-related behaviors or prevent overweight/obesity in children from socio-economically disadvantaged families of high-income countries: a systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023Pooled it
- Interventions in the first 1000 days to prevent childhood obesity: a systematic review and quantitative content analysis.BMC public health · 2022Pooled it
- Pooled it
- Addressing obesity in the first 1000 days in high risk infants: Systematic review.Maternal & child nutrition · 2021Pooled it
- Association of Protein Intake during the Second Year of Life with Weight Gain-Related Outcomes in Childhood: A Systematic Review.Nutrients · 2021Pooled it
- Associations between lifestyle interventions during pregnancy and childhood weight and growth: a systematic review and meta-analysis.The international journal of behavioral nutrition and physical activity · 2021Pooled it
- Understanding rapid infant weight gain prevention: a systematic review of quantitative and qualitative evidence.European journal of public health · 2020Pooled it
- A developmental cascade perspective of paediatric obesity: A systematic review of preventive interventions from infancy through late adolescence.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2020Pooled it
- Developing a core outcome set for childhood obesity prevention: A systematic review.Maternal & child nutrition · 2019Pooled it
- Infant formula feeding practices associated with rapid weight gain: A systematic review.Maternal & child nutrition · 2018Pooled it
- A qualitative systematic review of maternal infant feeding practices in transitioning from milk feeds to family foods.Maternal & child nutrition · 2017Pooled it
- Interventions for Childhood Obesity in the First 1,000 Days A Systematic Review.American journal of preventive medicine · 2016Pooled it
- Systematic review of randomised controlled trials of interventions that aim to reduce the risk, either directly or indirectly, of overweight and obesity in infancy and early childhood.Maternal & child nutrition · 2016Pooled it
- 'Saga Stories in health talks' for health promotion in Swedish child healthcare: results from a cluster-randomised hybrid type 1 effectiveness-implementation study.BMC public health · 2025Trial
- A randomized controlled trial to test the efficacy of a brief Triple P discussion group to increase healthy feeding practices and reduce risk factors for infant obesity.Journal of pediatric psychology · 2024Trial
- Effects of responsive breastfeeding intervention on breastfeeding and infant growth in China: A randomised controlled trial.Maternal & child nutrition · 2024Trial
58 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The risk factors for childhood overweight and obesity are known and can be identified antenatally or during infancy, however, the majority of effective interventions are designed for older children. This review identified interventions designed to reduce the risk of overweight/obesity that were delivered antenatally or during the first 2 years of life, with outcomes reported from birth to 7 years of age. Six electronic databases were searched for papers reporting randomised controlled trials of interventions published from January 1990 to September 2013. A total of 35 eligible studies were identified, describing 27 unique trials of which 24 were behavioural and three were non-behavioural. The 24 behavioural trials were categorised by type of intervention: (1) nutritional and/or responsive feeding interventions targeted at parents of infants, which improved feeding practices and had some impact on child weight (n = 12); (2) breastfeeding promotion and lactation support for mothers, which had a positive effect on breastfeeding but not child weight (n = 5); (3) parenting and family lifestyle (n = 4); and (4) maternal health (n = 3) interventions that had some impact on feeding practices but not child weight. The non-behavioural trials comprised interventions manipulating formula milk composition (n = 3). Of these, lower/hydrolysed protein formula milk had a positive effect on weight outcomes. Interventions that aim to improve diet and parental responsiveness to infant cues showed most promise in terms of self-reported behavioural change. Despite the known risk factors, there were very few intervention studies for pregnant women that continue during infancy which should be a priority for future research.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.