ArticleMagma (New York, N.Y.)2015
Localized semi-LASER dynamic (31)P magnetic resonance spectroscopy of the soleus during and following exercise at 7 T.
Article in Magma (New York, N.Y.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Pooled it
- Dynamic multivoxel-localizedNMR in biomedicine · 2018Trial
- Skeletal muscle ATP synthesis and cellular H(+) handling measured by localized (31)P-MRS during exercise and recovery.Scientific reports · 2016Trial
- Post Activation Potentiation Is Greater in Human Triceps Brachii Versus Triceps Surae Muscles.Muscle & nerve · 2026Article
- A Novel 9-ChannelMagnetic resonance in medicine · 2026Article
- Observational
- Chemical exchange saturation transfer imaging of creatine, phosphocreatine, and protein arginine residue in tissues.NMR in biomedicine · 2023Review
- Utilizing Dynamic Phosphorous-31 Magnetic Resonance Spectroscopy for the Early Detection of Acute Compartment Syndrome: A Pilot Study on Rats.Diagnostics (Basel, Switzerland) · 2021Article
- Urolithin A augments angiogenic pathways in skeletal muscle by bolstering NADScientific reports · 2020Article
- InterleavedMagnetic resonance in medicine · 2020Article
- Energy Expenditure of Dynamic Submaximal Human Plantarflexion Movements: Model Prediction and Validation byFrontiers in bioengineering and biotechnology · 2020Article
- Dynamic phosphocreatine imaging with unlocalized pH assessment of the human lower leg muscle following exercise at 3T.Magnetic resonance in medicine · 2018Article
- Topical tissue nano-transfection mediates non-viral stroma reprogramming and rescue.Nature nanotechnology · 2017Article
- In-vivoAnalytical biochemistry · 2017Review
- Interleaved multivoxelMagnetic resonance in medicine · 2017Article
- DynamicNMR in biomedicine · 2016Article
- Simultaneous and interleaved acquisition of NMR signals from different nuclei with a clinical MRI scanner.Magnetic resonance in medicine · 2016Article
- Magnetic Resonance Imaging of Phosphocreatine and Determination of BOLD Kinetics in Lower Extremity Muscles using a Dual-Frequency Coil Array.Scientific reports · 2016Article
- Skeletal muscle alkaline Pi pool is decreased in overweight-to-obese sedentary subjects and relates to mitochondrial capacity and phosphodiester content.Scientific reports · 2016Article
- Feasibility and repeatability of localized (31) P-MRS four-angle saturation transfer (FAST) of the human gastrocnemius muscle using a surface coil at 7 T.NMR in biomedicine · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
Abstract
objectivesThis study demonstrates the applicability of semi-LASER localized dynamic (31)P MRS to deeper lying areas of the exercising human soleus muscle (SOL). The effect of accurate localization and high temporal resolution on data specificity is investigated. MATERIALS AND
methodsTo achieve high signal-to-noise ratio (SNR) at a temporal resolution of 6 s, a custom-built human calf coil array was used at 7T. The kinetics of phosphocreatine (PCr) and intracellular pH were quantified separately in SOL and gastrocnemius medialis (GM) muscle of nine volunteers, during rest, plantar flexion exercise, and recovery.
resultsThe average SNR of PCr at rest was [Formula: see text] in SOL ([Formula: see text] in GM). End exercise PCr depletion in SOL ([Formula: see text] %) was far lower than in GM ([Formula: see text] %). The pH in SOL increased rapidly and, in contrast to GM, remained elevated until the end of exercise.
conclusion(31)P MRS in single-shots every 6 s localized in the deeper-lying SOL enabled quantification of PCr recovery times at low depletions and of fast pH changes, like the initial rise. Both high temporal resolution and accurate spatial localization improve specificity of Pi and, thus, pH quantification by avoiding multiple, and potentially indistinguishable sources for changing the Pi peak shape.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.