ArticleIntensive care medicine2015
Long-term neuropsychological outcomes in children and adolescents after cardiac arrest.
Article in Intensive care medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 61 citations in OpenAlex.
- Randomized clinical trial on the effects of early cognitive interventions for children with acquired brain injury.Scientific reports · 2025Trial
- Neuropsychological Outcomes of Children 1 Year After Pediatric Cardiac Arrest: Secondary Analysis of 2 Randomized Clinical Trials.JAMA neurology · 2018Trial
- Neurobehavioural outcomes in children after In-Hospital cardiac arrest.Resuscitation · 2018Trial
- Trial
- Family Burden After Out-of-Hospital Cardiac Arrest in Children.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2016Trial
- Trial
- One year quality of life outcomes in critically ill children: a multicenter prospective cohort study.Critical care (London, England) · 2026Article
- Current practice in pediatric post-cardiac arrest care: a national survey among Italian pediatric intensivists.Resuscitation plus · 2025Article
- An 18-year, single centre, retrospective study of long-term neurological outcomes in paediatric submersion-related cardiac arrests.Resuscitation plus · 2024Article
- An open window: the crucial role of the gut-brain axis in neurodevelopmental outcomes post-neurocritical illness.Frontiers in pediatrics · 2024Article
- Long-term follow-up in pediatric intensive care-a narrative review.Frontiers in pediatrics · 2024Review
- Follow-up after PICU discharge for patients with acquired brain injury: the role of an abbreviated neuropsychological evaluation and a return-to-school program.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2023Article
- Back to School: Academic Functioning and Educational Needs among Youth with Acquired Brain Injury.Children (Basel, Switzerland) · 2022Review
- Long-Term Outcomes after Non-Traumatic Out-of-Hospital Cardiac Arrest in Pediatric Patients: A Systematic Review.Journal of clinical medicine · 2022Review
- Cognitive and Psychological Outcomes Following Pediatric Cardiac Arrest.Frontiers in pediatrics · 2022Review
- Neuropsychological and Psychosocial Functioning of Children with Perinatal HIV-Infection in The Netherlands.Viruses · 2021Article
- Developmental Outcome in Infants with Cardiovascular Disease After Cardiopulmonary Resuscitation: A Pilot Study.Journal of clinical psychology in medical settings · 2019Article
- Early EEG Features for Outcome Prediction After Cardiac Arrest in Children.Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society · 2019Observational
- The association of early post-resuscitation hypotension with discharge survival following targeted temperature management for pediatric in-hospital cardiac arrest.Resuscitation · 2019Observational
- Observational
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeResearch into neuropsychological functioning of survivors of cardiac arrest (CA) in childhood is scarce. We sought to assess long-term neuropsychological functioning in children and adolescents surviving CA.
methodsNeuropsychological follow-up study involving all consecutive children surviving CA between January 2002 and December 2011. Intelligence (IQ), language, attention, memory, visual-spatial, and executive functioning were assessed with internationally validated, neuropsychological tests and questionnaires. Scores were compared with Dutch normative data.
resultsOf 107 eligible children, 47 who visited the outpatient clinic (median follow-up interval: 5.6 years) were analyzed. Fifty-five percent had an in-hospital CA, 86% a non-shockable rhythm, and 49% a respiratory-related etiology. CA survivors scored significantly worse on full-scale IQ (mean = 87.3), verbal IQ (mean = 92.7), performance IQ (mean = 85.6), verbal comprehension index (mean = 93.4), perceptual organization index (mean = 83.8), and processing speed index (mean = 91.1), than the norm population (mean IQ = 100). On neuropsychological tests, compared with norms, respectively adjusted for IQ, significantly worse scores were found on visual memory, significantly better on verbal memory (recognition), and comparable outcomes on visual-motor integration, attention, other measures of verbal memory, and executive functioning. On questionnaires, parents reported better executive functioning than the norm, but teachers reported more problems in planning/organizing skills.
conclusionsLong-term neuropsychological assessment of CA survivors showed significant weaknesses, but also relatively intact functioning. As deficits in IQ, memory and executive functioning have significant impact on the child, long-term follow-up and neuropsychological support of CA survivors is warranted.
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