ReviewEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2015
Standardised studies on Molar Incisor Hypomineralisation (MIH) and Hypomineralised Second Primary Molars (HSPM): a need.
Review in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 97 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Association Between MIH and HSPM
Prevalence of Hypomineralized Second Primary Molars and Its Association With Hypomineralized Primary Canines In A Group of Egyptian Children: A Cross-Sectional Study.
Who cites it
97 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Global prevalence of hypomineralised second primary molars: an updated systematic review with a meta-analysis.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Pooled it
- Prevalence of molar-incisor hypomineralisation (MIH) in children in the Gulf Cooperation Council countries: a systematic review and meta-analysis.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Pooled it
- Which diagnostic tools and criteria to use for diagnosis of HSPM and MIH? A systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Pooled it
- Diagnostic Indices for Epidemiological Assessment of Molar Incisor Hypomineralization: A Systematic Review.Calcified tissue international · 2026Pooled it
- Association of Molar Incisor Hypomineralization with Hypomineralized Second Primary Molars: An Updated Systematic Review with a Meta-Analysis and Trial Sequential Analysis.Caries research · 2025Pooled it
- Does information about MIH on dental homepages in Germany offer high quality? A systematic search and analysis.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2024Pooled it
- Is there a rise of prevalence for Molar Incisor Hypomineralization? A meta-analysis of published data.BMC oral health · 2024Pooled it
- Association between respiratory diseases and molar-incisor hypomineralization: A systematic review and meta-analysis.Frontiers in medicine · 2022Pooled it
- Maternal vitamin D status in pregnancy and molar incisor hypomineralisation and hypomineralised second primary molars in the offspring at 7-9 years of age: a longitudinal study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2022Trial
- Eighteen-month clinical performance of composite resin restorations with two different adhesive systems for molars affected by molar incisor hypomineralization.Clinical oral investigations · 2017Trial
- Knowledge and management of hypomineralisation of second primary molars among Brazilian dentists: a cross-sectional study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Prevalence and characteristics of hypomineralised second primary molars in Irish school children.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Increasing Diagnosis of Enamel Hypomineralisation in a Sample of More Than 70 000 Children in the City of Zurich: Repeated Cross-Sectional Prevalence Analyses and a Retrospective Longitudinal Cohort Analysis.International journal of paediatric dentistry · 2026Observational
- Prevalence and Associated Factors of Hypomineralised Second Primary Molars in 3-5-Year-Old Children in Aydın, Türkiye.Oral health & preventive dentistry · 2026Article
- Comparative label-free quantitative proteomics of hypomineralised second primary molars (HSPM) and molar incisor hypomineralisation (MIH) reveals divergent enamel protein signatures underpinning distinct pathogenic mechanisms.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Molar-Incisor Hypomineralisation in Children: The Essential Role of Paediatricians.Journal of paediatrics and child health · 2026Review
- Prevalence and etiology of molar incisor hypomineralization and hypomineralized second primary molars in children, Uşak Region, Turkey.BMC oral health · 2026Article
- Distribution and Clinical Characteristics of MIH in Schoolchildren From the Central Peruvian Jungle: A Cross‑Sectional Study.International journal of dentistry · 2026Article
- A proteomics approach to understand the hypomineralisation of second primary molars (HSPM). In-vitro study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025Article
- Aetiological factors in molar incisor hypomineralisation: a case-control study from Salamanca, Spain.Italian journal of pediatrics · 2025Observational
37 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In November 2014, a review of literature concerning prevalence data of Molar Incisor Hypomineralisation (MIH) and Hypomineralised Second Primary Molars (HSPM) was performed. A search of PubMed online databases was conducted for relevant articles published until November 2014. The reference lists of all retrieved articles were hand-searched. Studies were included after assessing the eligibility of the full-text article. Out of 1078 manuscripts, a total of 157 English written publications were selected based on title and abstract. Of these 157, 60 were included in the study and allocated as 52 MIH and 5 HSPM, and 3 for both MIH and HSPM. These studies utilised the European Academy of Paediatric Dentistry judgment criteria, the modified index of developmental defects of enamel (mDDE) and self-devised criteria, and demonstrated a wide variation in the reported prevalence (MIH 2.9-44 %; HSPM 0-21.8 %). Most values mentioned were representative for specific areas. More studies were performed in cities compared with rural areas. A great variation was found in calibration methods, number of participants, number of examiners and research protocols between the studies. The majority of the prevalence studies also investigated possible aetiological factors. To compare MIH and HSPM prevalence and or aetiological data around the world, standardisation of such studies seems essential. Standardisation of the research protocol should include a clearly described sample of children (minimum number of 300 for prevalence and 1000 for aetiology studies) and use of the same calibration sets and methods whereas aetiological studies need to be prospective in nature. A standardised protocol for future MIH and HSPM prevalence and aetiology studies is recommended.
Indexed as
Identifiers
25894247What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.