ReviewInternational journal of molecular sciences2015
Potential biological applications of bio-based anacardic acids and their derivatives.
Review in International journal of molecular sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed, 153 citations in OpenAlex.
- Single-nucleus sequencing and spatial metabolomics analysis reveal the regulatory mechanism of ginkgolic acid biosynthesis in the episperm ofHorticulture research · 2026Article
- Unlocking the Neuroprotective Potential ofAntioxidants (Basel, Switzerland) · 2026Review
- Synthesis of Isochromans From Anacardic Acids Obtained From Cashew Nutshell Liquid (CNSL) and Their Antimicrobial Activity.Chemistry & biodiversity · 2026Article
- Transforming extracted cashew nut shell into biochar and its application as soil amender for jute mallow (Corchorus olitorius L.) cultivation.Scientific reports · 2026Article
- Exploring the Potential of Anacardic Acid, its Natural and Synthetic Analogues, and Nanoformulations as a Potential Antibacterial Agent, including Multidrug-resistant Bacteria: A Comprehensive Review.Mini reviews in medicinal chemistry · 2026Review
- The vicious cycle of neuroinflammation and ferroptosis in depression: mechanisms and therapeutic targets.Frontiers in neuroscience · 2026Review
- Article
- Exploring the Therapeutic Value of Some Vegetative Parts ofMolecules (Basel, Switzerland) · 2025Review
- Understanding the effects of pre-treatment and extraction methods on lipid fingerprint of cashew nut shell liquid (CNSL) by non-targeted lipidomics analysis.Scientific reports · 2025Article
- Study of Electrochemical Transformation of Anacardic Acid from Cashew (Molecules (Basel, Switzerland) · 2025Article
- The adsorption behavior at the air/water interface of saturated cardanol nonionic surfactants through molecular dynamic simulations.Journal of molecular modeling · 2025Article
- From Nature to Drug: Overview and CADD Approach of Anacardic Acid to Propose their Biological Potential.Current topics in medicinal chemistry · 2025Review
- A comprehensive review on sustainable surfactants from CNSL: chemistry, key applications and research perspectives.RSC advances · 2024Review
- Antagonistic effectiveness of Anacardium occidentale leaf extract on lead-acetate exposure-induced hepatorenal toxicity in rats.Environmental analysis, health and toxicology · 2023Article
- Advances in Nanomaterials Based on Cashew Nut Shell Liquid.Nanomaterials (Basel, Switzerland) · 2023Review
- Sulfonamide derived from anacardic acid as potential antichagasic: a theoretical approach based on molecular docking, molecular dynamics, and density functional theory calculations.Journal of molecular modeling · 2023Article
- Review
- Physicochemical and microbiological assessment of a dental adhesive doped with cashew nut shell liquid.Odontology · 2022Article
- Sustainable multifunctional phenolic lipids as potential therapeutics in Dentistry.Scientific reports · 2022Article
- CNSL, a Promising Building Blocks for Sustainable Molecular Design of Surfactants: A Critical Review.Molecules (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cashew nut shells (CNS), which are agro wastes from cashew nut processing factories, have proven to be among the most versatile bio-based renewable materials in the search for functional materials and chemicals from renewable resources. CNS are produced in the cashew nut processing process as waste, but they contain cashew nut shell liquid (CNSL) up to about 30-35 wt. % of the nut shell weight depending on the method of extraction. CNSL is a mixture of anacardic acid, cardanol, cardol, and methyl cardol, and the structures of these phenols offer opportunities for the development of diverse products. For anacardic acid, the combination of phenolic, carboxylic, and a 15-carbon alkyl side chain functional group makes it attractive in biological applications or as a synthon for the synthesis of a multitude of bioactive compounds. Anacardic acid, which is about 65% of a CNSL mixture, can be extracted from the agro waste. This shows that CNS waste can be used to extract useful chemicals and thus provide alternative green sources of chemicals, apart from relying only on the otherwise declining petroleum based sources. This paper reviews the potential of anacardic acids and their semi-synthetic derivatives for antibacterial, antitumor, and antioxidant activities. The review focuses on natural anacardic acids from CNS and other plants and their semi-synthetic derivatives as possible lead compounds in medicine. In addition, the use of anacardic acid as a starting material for the synthesis of various biologically active compounds and complexes is reported.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.