Evidence map›Paper›PMID 25893708›Full record

ReviewFunctional & integrative genomics2015

Genome-wide identification and characterization of Fox genes in the silkworm, Bombyx mori.

JiangBo Song, ZhiQuan Li, XiaoLing Tong, Cong Chen, Min Chen, Gang Meng, Peng Chen, ChunLin Li, YaQun Xin, TingTing Gai and 2 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Functional & integrative genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  5. The Journal of biological chemistry · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

JiangBo SongState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, 400716, China.
ZhiQuan Li
XiaoLing Tong
Cong Chen
Min Chen
Gang Meng
Peng Chen
ChunLin Li
YaQun Xin
TingTing Gai
FangYin Dai
Cheng Lu
Southwest University · CNState Key Laboratory of Silkworm Genomic Biology

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The forkhead box (Fox) transcription factor family has a characteristic of forkhead domain, a winged DNA-binding domain. The Fox genes have been classified into 23 subfamilies, designated FoxA to FoxS, of which the FoxR and FoxS subfamilies are specific to vertebrates. In this review, using whole-genome scanning, we identified 17 distinct Fox genes distributed on 13 chromosomes of the silkworm, Bombyx mori. A phylogenetic tree showed that the silkworm Fox genes could be classified into 13 subfamilies. The FoxK subfamily is specifically absent from the silkworm, although it is present in other lepidopteran insects, including Danaus plexippus and Heliconius melpomene. Microarray data revealed that the Fox genes have distinct expression patterns in the tissues on day 3 of the 5th instar larva. A Gene Ontology analysis suggested that the Fox genes have roles in cellular components, molecular functions, and biological processes, except in pore complex biogenesis. An analysis of the selective pressure on the proteins indicated that most of the amino acid sites in the Fox proteins are undergoing strong purifying selection. Here, we summarize the general characteristics of the Fox genes in the silkworm, which should support further functional studies of the silkworm Fox proteins.

Indexed as

Amino Acid SequenceAnimalsBombyxChromosome MappingChromosomes, InsectForkhead Transcription FactorsGene ExpressionGene OntologyGenome, InsectHumansInsect ProteinsMolecular Sequence DataPhylogenySelection, GeneticForkhead Transcription FactorsInsect Proteins

Identifiers

PMID25893708
OpenAlexW2084032654

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.