Evidence map›Paper›PMID 25893702›Full record

ArticleThe Consultant pharmacist : the journal of the American Society of Consultant Pharmacists2015

Racial differences in anticholinergic use among community-dwelling elders.

Maria Felton, Joseph T Hanlon, Subashan Perera, Joshua M Thorpe, Zachary A Marcum

Open access · greenAbstract read
In one paragraph

Article in The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

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  12. Concordance Between Anticholinergic Burden Scales.Journal of the American Geriatrics Society · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Maria FeltonSchool of Pharmacy at the University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Joseph T Hanlon
Subashan Perera
Joshua M Thorpe
Zachary A Marcum
VA Pittsburgh Healthcare System · USUniversity of Pittsburgh · US

Funding

VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Caterina Rosano · 2004 to 2026
$28.6M
Pitt Integrated Clinical and Geroscience Research Training ProgramT32AG021885 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Aditi U Gurkar · 2003 to 2026
$6.7M
End of Life in the Very OldR01NR012459 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ALBERT, STEVEN M, LUNNEY, JUNE R · 2011 to 2015
$2.7M
Longitudinal Impact of CNS Polypharmacy on Geriatric SyndromesR01AG027017 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HANLON, JOSEPH T · 2006 to 2012
$801k
UPITT Program for Pharmaceutical Outcomes Research in AgingK07AG033174 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HANLON, JOSEPH T · 2009 to 2013
$461k
Intramural NIH HHSNIA NIH HHS K07 AG033174NIA NIH HHS P30 AG024827NIA NIH HHS R01 AG027017NIA NIH HHS T32 AG021885NINR NIH HHS R01 NR012459
6 · The paper itself

Abstract

objectiveFew studies have examined racial differences in potentially inappropriate medication use. The objective of this study was to examine racial disparities in using prescription and/or nonprescription anticholinergics, a type of potentially inappropriate medication, over time.

designLongitudinal.

settingData from the Health, Aging, and Body Composition Study (years 1, 5, and 10).

participantsThree thousand fifty-five community-dwelling older adults, both blacks and whites, at year 1.

main outcome measureHighly anticholinergic medication use per the 2012 American Geriatrics Society Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults.

resultsBlacks represented 41.4% of the participants at year 1. At year 1, 13.4% of blacks used an anticholinergic medication compared with 17.8% of whites, and this difference persisted over the ensuing 10-year period. Diphenhydramine was the most common anticholinergic medication reported at baseline and year 5, and meclizine at year 10, for both races. Controlling for demographics, health status, and access to care factors, blacks were 24% to 45% less likely to use any anticholinergics compared with whites over the years considered (all P < 0.05).

conclusionThe use of prescription and/or nonprescription anticholinergic medications was less common in older blacks than whites over a 10-year period, and the difference was unexplained by demographics, health status, and access to care.

Indexed as

AgedBlack PeopleCholinergic AntagonistsDrug UtilizationFemaleHumansMaleWhite PeopleCholinergic Antagonists

Identifiers

PMID25893702
PMCPMC4405895
OpenAlexW2335418062

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.