Evidence map›Paper›PMID 25893097›Full record

ArticleRegeneration (Oxford, England)2015

Distal Regeneration Involves the Age Dependent Activity of Branchial Sac Stem Cells in the Ascidian

William R Jeffery

Abstract read
In one paragraph

Article in Regeneration (Oxford, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Integrin-Alpha-6+ Cells Are Responsible for Blastema Formation During Oral Siphon Regeneration in Ciona robusta.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  3. Article
  4. The salamander blastema within the broader context of metazoan regeneration.Frontiers in cell and developmental biology · 2023
    Review
  5. A pan-metazoan concept for adult stem cells: the wobbling Penrose landscape.Biological reviews of the Cambridge Philosophical Society · 2022
    Article
  6. Studying Regeneration in Ascidians: An Historical Overview.Methods in molecular biology (Clifton, N.J.) · 2022
    Review
  7. The Diverse Manifestations of Regeneration and Why We Need to Study Them.Cold Spring Harbor perspectives in biology · 2021
    Article
  8. Article
  9. Article
  10. Animal regeneration in the era of transcriptomics.Cellular and molecular life sciences : CMLS · 2021
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

William R JefferyEugene Bell Center for Regenerative Biology and Tissue Engineering, Marine Biological Laboratory, Woods Hole, MA 02543; Department of Biology, University of Maryland, College Park, MD, 20742 USA.

Funding

The Tunicate Ciona: A New Model for the Effects of Aging on Tissue RegenerationR01AG037918 · NIA · UNIV OF MARYLAND, COLLEGE PARK · PI JEFFERY, WILLIAM R · 2010 to 2014
$1.5M
NIA NIH HHS R01 AG037918
6 · The paper itself

Abstract

Tunicates have high capacities for regeneration but the underlying mechanisms and their relationship to life cycle progression are not well understood. Here we investigate the regeneration of distal structures in the ascidian tunicate

Indexed as

agingbranchial sacCiona intestinalisdistal regenerationstem cells

Identifiers

PMID25893097
PMCPMC4396878

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.