ArticleScientific reports2015
Metabolite localization in living drosophila using High Resolution Magic Angle Spinning NMR.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 31 citations in OpenAlex.
- Live Metabolomics with NMR.Analytical chemistry · 2026Review
- The Power of Drosophila in Modeling Cancer Cachexia.Advances in experimental medicine and biology · 2025Review
- Tracking Metabolite Variations during the Degradation of Vegetables in Rice Bran Bed with Intact-State Nuclear Magnetic Resonance Spectroscopy.Metabolites · 2024Article
- Metabolomics in Cell Biology.Handbook of experimental pharmacology · 2023Article
- Solid-State NMR Investigations of Extracellular Matrixes and Cell Walls of Algae, Bacteria, Fungi, and Plants.Chemical reviews · 2022Review
- Mild Muscle Mitochondrial Fusion Distress ExtendsInternational journal of molecular sciences · 2021Article
- HR-MAS NMR Applications in Plant Metabolomics.Molecules (Basel, Switzerland) · 2021Review
- Spatial molecular-dynamically ordered NMR spectroscopy of intact bodies and heterogeneous systems.Communications chemistry · 2020Article
- Spatially-resolved metabolic profiling of living Drosophila in neurodegenerative conditions usingScientific reports · 2020Article
- ContinuousFrontiers in molecular biosciences · 2019Article
- In-Vivo NMR Spectroscopy: A Powerful and Complimentary Tool for Understanding Environmental Toxicity.Metabolites · 2018Review
- TheDisease models & mechanisms · 2018Article
- Metabolomics with Nuclear Magnetic Resonance Spectroscopy in a Drosophila melanogaster Model of Surviving Sepsis.Metabolites · 2016Article
- In-Cell Solid-State NMR: An Emerging Technique for the Study of Biological Membranes.Biophysical journal · 2015Review
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have developed new methods enabling in vivo localization and identification of metabolites through their (1)H NMR signatures, in a drosophila. Metabolic profiles in localized regions were obtained using HR-MAS Slice Localized Spectroscopy and Chemical Shift Imaging at high magnetic fields. These methods enabled measurement of metabolite contents in anatomic regions of the fly, demonstrated by a decrease in β-alanine signals in the thorax of flies showing muscle degeneration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.