Evidence map›Paper›PMID 25892151›Full record

Trial reportGeneral hospital psychiatry

Improving work outcomes of dysthymia (persistent depressive disorder) in an employed population.

David A Adler, Debra Lerner, Zachary L Visco, Annabel Greenhill, Hong Chang, Elina Cymerman, Francisca Azocar, William H Rogers

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in General hospital psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Interventions to improve return to work in depressed people.The Cochrane database of systematic reviews · 2020
    Pooled it
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

David A AdlerProgram on Health, Work, and Productivity, Tufts Medical Center, 800 Washington Street, #345, Boston, MA 02111, USA; Tufts University School of Medicine, 145 Harrison Avenue, Boston, MA 02111, USA; Department of Psychiatry, Tufts Medical Center, 800 Washington Street, #345, Boston, MA 02111, USA. Electronic address: dadler@tuftsmedicalcenter.org.
Debra LernerProgram on Health, Work, and Productivity, Tufts Medical Center, 800 Washington Street, #345, Boston, MA 02111, USA; Tufts University School of Medicine, 145 Harrison Avenue, Boston, MA 02111, USA; Department of Psychiatry, Tufts Medical Center, 800 Washington Street, #345, Boston, MA 02111, USA. Electronic address: dlerner@tuftsmedicalcenter.org.
Zachary L ViscoProgram on Health, Work, and Productivity, Tufts Medical Center, 800 Washington Street, #345, Boston, MA 02111, USA. Electronic address: zvisco@tuftsmedicalcenter.org.
Annabel GreenhillProgram on Health, Work, and Productivity, Tufts Medical Center, 800 Washington Street, #345, Boston, MA 02111, USA. Electronic address: agreenhill@tuftsmedicalcenter.org.
Hong ChangProgram on Health, Work, and Productivity, Tufts Medical Center, 800 Washington Street, #345, Boston, MA 02111, USA. Electronic address: hchang@tuftsmedicalcenter.org.
Elina CymermanDepartment of Psychiatry, Tufts Medical Center, 800 Washington Street, #345, Boston, MA 02111, USA. Electronic address: ecymerman@tuftsmedicalcenter.org.
Francisca AzocarOptumHealth, 425 Market Street, 14th Floor San Francisco, CA 94105, USA. Electronic address: francisca.azocar@optum.com.
William H RogersProgram on Health, Work, and Productivity, Tufts Medical Center, 800 Washington Street, #345, Boston, MA 02111, USA. Electronic address: whrogers@tuftsmedicalcenter.org.
Tufts Medical Center · USTufts University · USOptum (United States) · US

Funding

Preventing Mid- and Later-Life Work Limitations: Community-Based Depression CareR01AG033125 · NIA · TUFTS MEDICAL CENTER · PI LERNER, DEBRA · 2009 to 2012
$2.2M
NIA NIH HHS R01 AG033125NIA NIH HHS R01AG033125
6 · The paper itself

Abstract

objectiveTo test the effectiveness of a work-focused intervention (WFI) on the work outcomes of employed adults with dysthymia.

methodThis subgroup analysis from a randomized controlled trial compares an initial sample of 167 employees (age: ≥45 years), screened for dysthymia using the PC-SAD without current major depressive disorder randomized to WFI (n=85) or usual care (UC) (n=82). Study sites included 19 employers and five additional organizations. Telephone-based WFI counseling (eight, twice monthly 50-min sessions) provided work coaching and modification, care coordination and cognitive behavioral therapy. Adjusted mixed effects models compared the WFI vs. UC group preintervention to 4-month postintervention change in at-work limitations measured by the Work Limitations Questionnaire. Secondary outcome analysis compared the change in self-reported absences and depression symptom severity (Patient Health Questionnaire PHQ-9 scores).

resultsWork productivity loss scores improved 43.0% in the WFI group vs. 4.8% in UC (difference in change: P<.001). Absence days declined by 58.3% in WFI vs. 0.0% in UC (difference in change: P=.09). Mean PHQ-9 depression symptom severity declined 44.2% in WFI vs. 5.3% in UC (difference in change: P<.001).

conclusionAt 4 months, the WFI was more effective than UC on two of the three outcomes. It could be an important mental and functional health improvement resource for the employed dysthymic population.

Indexed as

AbsenteeismEfficiencyEmploymentTelephoneCognitive Behavioral TherapyDysthymic DisorderFemaleHumansMaleMiddle AgedOccupational HealthSick LeaveTreatment OutcomeDysthymiaEconomic issuesMood disorderOutcome studiesWork productivity

Identifiers

PMID25892151
PMCPMC4457606
OpenAlexW2003346040

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.