ReviewAnalytica chimica acta2015
Protein adsorption onto nanomaterials for the development of biosensors and analytical devices: a review.
Review in Analytica chimica acta, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Direct measurement of protein dipoles reveals the mechanism for like-charge adsorption on silica.Nature communications · 2026Article
- Emerging Nanobiochar -Hydrogel Therapeutic Systems: Redox Modulation, Biointerface Interactions, and Critical Gaps in In Vitro Evaluation.Gels (Basel, Switzerland) · 2026Review
- Engineering Thermoresponsive Biointerfaces Using Graft-To Strategies: Connecting Polymer Architecture to Temperature-Dependent Surface Wettability.Macromolecules · 2026Article
- Site-Specific Immobilization of ZNRF3 Reveals the Importance of Target Structural Integrity on Macrocyclic Peptide Selections.ACS chemical biology · 2026Article
- Protein Adsorption Kinetics on Silica: Theoretical Modeling and Experiments.Langmuir : the ACS journal of surfaces and colloids · 2026Article
- A nucleic acid-based electrochemical detection method forSensors & diagnostics · 2026Article
- Recent Advances in Electrochemical Biosensors for the Detection of Milk Adulterants.Biosensors · 2026Review
- Toward Rational Design of Ion-Exchange Nanofiber Membranes: Meso-Scale Computational Approaches.Membranes · 2025Review
- Covalent Attachment of Functional Proteins to Microfiber Surfaces via a General Strategy for Site-Selective Tetrazine Ligation.ACS applied materials & interfaces · 2024Article
- Development of a Multiplex HIV/TB Diagnostic Assay Based on the Microarray Technology.Biosensors · 2023Article
- Hemocompatibility of β-Cyclodextrin-Modified (Methacryloyloxy)ethyl Phosphorylcholine Coated Magnetic Nanoparticles.Biomolecules · 2023Article
- Signaling strategies of silver nanoparticles in optical and electrochemical biosensors: considering their potential for the point-of-care.Mikrochimica acta · 2023Review
- Fluorescent optotracers for bacterial and biofilm detection and diagnostics.Science and technology of advanced materials · 2023Review
- Article
- Low-cost and cleanroom-free prototyping of microfluidic and electrochemical biosensors: Techniques in fabrication and bioconjugation.Biomicrofluidics · 2021Review
- Protein Adsorption onto Modified Porous Silica by Single and Binary Human Serum Protein Solutions.International journal of molecular sciences · 2021Article
- Mechanism of Myoglobin Molecule Adsorption on Silica: QCM, OWLS and AFM Investigations.International journal of environmental research and public health · 2021Article
- A Fluidics-Based Biosensor to Detect and Characterize Inhibition Patterns of Organophosphate to Acetylcholinesterase in Food Materials.Micromachines · 2021Article
- Carbon cloth-based immunosensor for detection of 25-hydroxy vitamin DMikrochimica acta · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
An important consideration for the development of biosensors is the adsorption of the biorecognition element to the surface of a substrate. As the first step in the immobilization process, adsorption affects most immobilization routes and much attention is given into the research of this process to maximize the overall activity of the biosensor. The use of nanomaterials, specifically nanoparticles and nanostructured films, offers advantageous properties that can be fine-tuned to maximize interactions with specific proteins to maximize activity, minimize structural changes, and enhance the catalytic step. In the biosensor field, protein-nanomaterial interactions are an emerging trend that span across many disciplines. This review addresses recent publications about the proteins most frequently used, their most relevant characteristics, and the conditions required to adsorb them to nanomaterials. When relevant and available, subsequent analytical figures of merits are discussed for selected biosensors. The general trend amongst the research papers allows concluding that the use of nanomaterials has already provided significant improvements in the analytical performance of many biosensors and that this research field will continue to grow.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.