Evidence map›Paper›PMID 25891292›Full record

ArticleMagnetic resonance in medicine2016

Accelerated and motion-robust in vivo T2 mapping from radially undersampled data using bloch-simulation-based iterative reconstruction.

Noam Ben-Eliezer, Daniel K Sodickson, Timothy Shepherd, Graham C Wiggins, Kai Tobias Block

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Simultaneous TMagnetic resonance in medicine · 2026
    Article
  2. High-resolution quantitative TImaging neuroscience (Cambridge, Mass.) · 2025
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  3. Article
  4. Improved myelin water imaging using BImaging neuroscience (Cambridge, Mass.) · 2024
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  5. Article
  6. Latest Advances in Image Acceleration: All Dimensions are Fair Game.Journal of magnetic resonance imaging : JMRI · 2023
    Review
  7. Article
  8. Article
  9. Golden-Angle Radial MRI: Basics, Advances, and Applications.Journal of magnetic resonance imaging : JMRI · 2022
    Review
  10. Review
  11. A review and experimental evaluation of deep learning methods for MRI reconstruction.The journal of machine learning for biomedical imaging · 2022
    Article
  12. Physics-based reconstruction methods for magnetic resonance imaging.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2021
    Review
  13. Article
  14. Article
  15. Quantitative TMagnetic resonance imaging · 2020
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Noam Ben-EliezerThe Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, New York, USA.
Daniel K SodicksonThe Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, New York, USA.
Timothy ShepherdThe Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, New York, USA.
Graham C WigginsThe Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, New York, USA.
Kai Tobias BlockThe Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, New York, USA.

Funding

TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Dmitry S Novikov · 2014 to 2026
$19.3M
Parallel MR Imaging: New Techniques and TechnologiesR01EB000447 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SODICKSON, DANIEL K · 2002 to 2012
$5.1M
NIBIB NIH HHS P41 EB017183NIBIB NIH HHS R01 EB000447
6 · The paper itself

Abstract

purposeDevelopment of a quantitative transverse relaxation time (T2)-mapping platform that operates at clinically feasible timescales by employing advanced image reconstruction of radially undersampled multi spin-echo (MSE) datasets.

methodsData was acquired on phantom and in vivo at 3 Tesla using MSE protocols employing radial k-space sampling trajectories. In order to overcome the nontrivial spin evolution associated with MSE protocols, a numerical signal model was precalculated based on Bloch simulations of the actual pulse-sequence scheme used in the acquisition process. This signal model was subsequently incorporated into an iterative model-based image reconstruction process, producing T2 and proton-density maps.

resultsT2 maps of phantom and in vivo brain were successfully constructed, closely matching values produced by a single spin-echo reference scan. High-resolution mapping was also performed for the spinal cord in vivo, differentiating the underlying gray/white matter morphology.

conclusionThe presented MSE data-processing framework offers reliable mapping of T2 relaxation values in a ∼ 5-minute timescale, free of user- and scanner-dependent variations. The use of radial k-space sampling provides further advantages in the form of high immunity to irregular physiological motion, as well as enhanced spatial resolutions, owing to its inherent ability to perform alias-free limited field-of-view imaging.

Indexed as

AdultAlgorithmsBrainComputer SimulationHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingPhantoms, Imagingmodel-based reconstructionquantitative MRIradial k-space samplingT2 mapping

Identifiers

PMID25891292
PMCPMC4609223

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.