Evidence map›Paper›PMID 25891050›Full record

ArticleAmerican journal of preventive medicine2015

Race-sex differences in the management of hyperlipidemia: the REasons for Geographic and Racial Differences in Stroke study.

Monika M Safford, Christopher M Gamboa, Raegan W Durant, Todd M Brown, Stephen P Glasser, James M Shikany, Richard M Zweifler, George Howard, Paul Muntner

Open access · greenAbstract read
In one paragraph

Article in American journal of preventive medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Monika M SaffordDepartments of Medicine, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address: msafford@uab.edu.
Christopher M GamboaEpidemiology, University of Alabama at Birmingham, Birmingham, Alabama.
Raegan W DurantDepartments of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Todd M BrownDepartments of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Stephen P GlasserDepartments of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
James M ShikanyDepartments of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Richard M ZweiflerSentara Healthcare & Department of Neurology, Eastern Virginia Medical School, Norfolk, Virginia.
George HowardBiostatistics, University of Alabama at Birmingham, Birmingham, Alabama.
Paul MuntnerEpidemiology, University of Alabama at Birmingham, Birmingham, Alabama.
University of Alabama at Birmingham · USEastern Virginia Medical School · US

Funding

VCID and Stroke in a Bi-racial National CohortU01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CUSHMAN, MARY, HOWARD, GEORGE · 2002 to 2022
$96.0M
Research Education CoreP30AG031054 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CLAY, OLIVIO J · 2007 to 2025
$11.6M
REGARDS - MI StudyR01HL080477 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LEVITAN, EMILY B, SAFFORD, MONIKA M · 2006 to 2020
$11.6M
Building Capacity for Cardiometabolic Outcomes ResearchK24HL111154 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI SAFFORD, MONIKA M · 2012 to 2015
$556k
NHLBI NIH HHS K24 HL111154NHLBI NIH HHS K24HL111154NHLBI NIH HHS R01 HL080477NHLBI NIH HHS R01HL080477NIA NIH HHS P30 AG031054NINDS NIH HHS U01 NS041588NINDS NIH HHS UO1NS041588
6 · The paper itself

Abstract

backgroundLipid management is less aggressive in blacks than whites and women than men. PURPOSE: To examine whether differences in lipid management for race-sex groups compared to white men are due to factors influencing health services utilization or physician prescribing patterns.

methodsBecause coronary heart disease (CHD) risk influences physician prescribing, Adult Treatment Panel III CHD risk categories were constructed using baseline data from REasons for Geographic And Racial Differences in Stroke study participants (recruited 2003-2007). Prevalence, awareness, treatment, and control of hyperlipidemia were examined for race-sex groups across CHD risk categories. Multivariable models conducted in 2013 estimated prevalence ratios adjusted for predisposing, enabling, and need factors influencing health services utilization.

resultsThe analytic sample included 7,809 WM; 7,712 white women; 4,096 black men; and 6,594 black women. Except in the lowest risk group, black men were less aware of hyperlipidemia than others. A higher percentage of white men in the highest risk group was treated (83.2%) and controlled (72.8%) than others (treatment, 68.6%-72.1%; control, 52.2%-65.5%), with black women treated and controlled the least. These differences remained significant after adjustment for predisposing, enabling, and need factors. Stratified analyses demonstrated that treatment and control were lower for other race-sex groups relative to white men only in the highest risk category.

conclusionsHyperlipidemia was more aggressively treated and controlled among white men compared with white women, black men, and especially black women among those at highest risk for CHD. These differences were not attributable to factors influencing health services utilization.

Indexed as

AgedAged, 80 and overDatabases, FactualFemaleGeographyHumansHyperlipidemiasMaleMiddle AgedSex FactorsStroke

Identifiers

PMID25891050
PMCPMC4422177
OpenAlexW2233621258

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.