ArticleThe Laryngoscope2015
Biomechanical evaluation of human and porcine auricular cartilage.
Article in The Laryngoscope, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
23 citing papers in PubMed, 52 citations in OpenAlex.
- Unconventional auricular reconstruction using controlled scaffold buckling and chondrogenic cocktail containing muscle-derived cells.Bioactive materials · 2026Article
- Precise ablation of cholesteatoma using a 445-nm diode laser.Scientific reports · 2026Article
- Innovative Approaches in Microtia Treatment: Advancements in Tissue Engineering and Scaffold Design.Annals of biomedical engineering · 2025Review
- Head and Neck 3D Bioprinting-A Review on Recent Advancements in Soft Tissue 3D Bioprinting and Medical Applications.Journal of functional biomaterials · 2025Review
- Age and Gender Related Variability in the Strength of Auricular Cartilage in Living Humans.Aesthetic plastic surgery · 2025Article
- Development and Characterization of Heparin-Containing Hydrogel/3D-Printed Scaffold Composites for Craniofacial Reconstruction.Annals of biomedical engineering · 2024Article
- Accessory tympanic plate ossicle: a new osteological entity.Forensic sciences research · 2024Article
- Hydrogel Based on Chitosan/Gelatin/Poly(Vinyl Alcohol) for In Vitro Human Auricular Chondrocyte Culture.Polymers · 2024Article
- Manufacture Dependent Differential Biodegradation of 3D Printed Shape Memory Polymers.Virtual and physical prototyping · 2024Article
- Article
- Upregulated desmin/integrin β1/MAPK axis promotes elastic cartilage regeneration with increased ECM mechanical strength.International journal of biological sciences · 2023Article
- Article
- Hybrid Three-Dimensional-Printed Ear Tissue Scaffold With Autologous Cartilage Mitigates Soft Tissue Complications.The Laryngoscope · 2021Article
- Preclinical assessment of clinically streamlined, 3D-printed, biocompatible single- and two-stage tissue scaffolds for ear reconstruction.Journal of biomedical materials research. Part B, Applied biomaterials · 2021Article
- Biofabrication of a shape-stable auricular structure for the reconstruction of ear deformities.Materials today. Bio · 2021Article
- Modulating nonlinear elastic behavior of biodegradable shape memory elastomer and small intestinal submucosa(SIS) composites for soft tissue repair.Journal of the mechanical behavior of biomedical materials · 2020Article
- Structure and mechanical properties of high-weight-bearing and low-weight-bearing areas of hip cartilage at the micro- and nano-levels.BMC musculoskeletal disorders · 2020Article
- Evaluation of human nasal cartilage nonlinear and rate dependent mechanical properties.Journal of biomechanics · 2020Article
- Auricle shaping using 3D printing and autologous diced cartilage.The Laryngoscope · 2019Article
- [Mechanical study of polyurethane elastomer and Medpor as the material of artificial auricular scaffold].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
objectives/hypothesisThe mechanical properties of normal auricular cartilage provide a benchmark against which to characterize changes in auricular structure/function due to genetic defects creating phenotypic abnormalities in collagen subtypes. Such properties also provide inputs/targets for auricular reconstruction scaffold design. Several studies report the biomechanical properties for septal, costal, and articular cartilage. However, analogous data for auricular cartilage are lacking. Therefore, our aim in this study was to characterize both whole-ear and auricular cartilage mechanics by mechanically testing specimens and fitting the results to nonlinear constitutive models. STUDY
designMechanical testing of whole ears and auricular cartilage punch biopsies.
methodsWhole human cadaveric ear and auricular cartilage punch biopsies from both porcine and human cartilage were subjected to whole-ear helix-down compression and quasistatic unconfined compression tests. Common hyperelastic constitutive laws (widely used to characterize soft tissue mechanics) were evaluated for their ability to represent the stress-strain behavior of auricular cartilage.
resultsLoad displacement curves for whole ear testing exhibited compliant linear behavior until after significant displacement where nonlinear stiffening occurred. All five commonly used two-term hyperelastic soft tissue constitutive models successfully fit both human and porcine nonlinear elastic behavior (mean R(2) fit >0.95).
conclusionsAuricular cartilage exhibits nonlinear strain-stiffening elastic behavior that is similar to other soft tissues in the body. The whole ear exhibits compliant behavior with strain stiffening at high displacement. The constants from the hyperelastic model fits provide quantitative baselines for both human and porcine (a commonly used animal model for auricular tissue engineering) auricular mechanics. LEVEL OF EVIDENCE: NA
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.