Evidence map›Paper›PMID 25890036›Full record

ArticleBMC veterinary research2015

Molecular characterization and phylogenetic analysis of transmissible gastroenteritis virus HX strain isolated from China.

Xiaoliang Hu, Nannan Li, Zhige Tian, Xin Yin, Liandong Qu, Juanjuan Qu

Open access · goldAbstract read
In one paragraph

Article in BMC veterinary research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 48 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Xiaoliang HuCollege of Resources and Environment, Northeast Agricultural University, Harbin, 150030, People's Republic of China. liang679@163.com.
Nannan LiCollege of Resources and Environment, Northeast Agricultural University, Harbin, 150030, People's Republic of China. 619483612@qq.com.
Zhige TianCollege of Wildlife Resources, Northeast Forestry University, Harbin, 150040, People's Republic of China. beishugege@126.com.
Xin YinCollege of Life Sciences, Northeast Agricultural University, Harbin, Harbin, 150030, People's Republic of China. 158584843@qq.com.
Liandong QuNational Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, 150001, People's Republic of China. qld@hvri.ac.cn.
Juanjuan QuCollege of Resources and Environment, Northeast Agricultural University, Harbin, 150030, People's Republic of China. juanjuanqu@126.com.
Northeast Agricultural University · CNChinese Academy of Agricultural Sciences · CNNortheast Forestry University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPorcine transmissible gastroenteritis virus (TGEV) is the major etiological agent of viral enteritis and severe diarrhea in suckling piglets. In China, TGEV has caused great economic losses, but its role in epidemic diarrhea is unclear. This study aims to reveal the etiological role of TGEV in piglet diarrhea via molecular characterization and phylogenetic analysis.

resultsA TGEV-HX strain was isolated from China, and its complete genome was amplified, cloned, and sequenced. Sequence analysis indicated that it was conserved in the 5' and 3'-non-translated regions, and there were no insertions or deletions in nonstructural genes, such as ORF1a, ORF1b, ORF3a, ORF3b, and ORF7, as well as in genes encoding structural proteins, such as the envelope (E), membrane (M), and nucleoprotein (N) proteins. Furthermore, the phylogenetic analysis indicated that the TGEV-HX strain was more similar to the TGEV Purdue cluster than to the Miller cluster.

conclusionsThe present study described the isolation and genetic characterization of a TGEV-HX strain. The detailed analysis of the genetic variation of TGEVs in China provides essential information for further understanding the evolution of TGEVs.

Indexed as

AnimalsBase SequenceChinaGastroenteritis, Transmissible, of SwineGenome, ViralMicroscopy, ElectronMolecular Sequence DataPhylogenyReverse Transcriptase Polymerase Chain ReactionSequence AlignmentSequence Homology, Amino AcidSequence Homology, Nucleic AcidSwineTransmissible gastroenteritis virusViral Envelope ProteinsViral Nonstructural ProteinsViral Envelope ProteinsViral Nonstructural ProteinsViral Structural Proteins

Identifiers

PMID25890036
PMCPMC4379598
OpenAlexW2017067774

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.