Evidence map›Paper›PMID 25889576›Full record

ArticleHealth and quality of life outcomes2015

Quality of life improved following in-patient substance use disorder treatment.

Adrian R Pasareanu, Anne Opsal, John-Kåre Vederhus, Øistein Kristensen, Thomas Clausen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Health and quality of life outcomes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Substance Use Disorder Treatment Outcomes: Methodological Overview of Metrics and Criteria.International journal of methods in psychiatric research · 2025
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  5. Examining quality of life by recovery status among college students with a history of substance use.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adrian R PasareanuAddiction Unit, Sørlandet Hospital HF, PO Box 416, 4604, Kristiansand, Norway. adrian.razvan.pasareanu@sshf.no.
Anne OpsalAddiction Unit, Sørlandet Hospital HF, PO Box 416, 4604, Kristiansand, Norway. anne.opsal@uia.no.
John-Kåre VederhusAddiction Unit, Sørlandet Hospital HF, PO Box 416, 4604, Kristiansand, Norway. john-kare.vederhus@sshf.no.
Øistein KristensenAddiction Unit, Sørlandet Hospital HF, PO Box 416, 4604, Kristiansand, Norway. oistein.kristensen@sshf.no.
Thomas ClausenAddiction Unit, Sørlandet Hospital HF, PO Box 416, 4604, Kristiansand, Norway. thomas.clausen@medisin.uio.no.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundQuality of life (QoL) is increasingly recognized as central to the broad construct of recovery in patients with substance use disorders (SUD). However, few longitudinal studies have evaluated changes in QoL after SUD treatment and included patients with SUD that were compulsorily hospitalized. This study aimed to describe QoL among in-patients admitted either voluntarily or compulsorily to hospitalization and to examine patterns and predictors of QoL at admission and at 6 months post treatment.

methodsThis prospective study followed 202 hospitalized patients with SUD that were admitted voluntarily (N=137) or compulsorily (N=65). A generic QoL questionnaire (QoL-5) was used to assess QoL domains. Regression analysis was conducted to identify associations with QoL at baseline and to examine predictors of change in QoL at a 6-month follow-up.

resultsThe majority of patients had seriously impaired QoL. Low QoL at baseline was associated with a high psychiatric symptom burden. Fifty-eight percent of patients experienced a positive QoL change at follow-up. Although the improvement in QoL was significant, it was considered modest (a mean 0.06 improvement in QoL-5 scores at follow-up; 95% confidence interval: 0.03 - 0.09; p<0.001). Patients admitted voluntarily and compulsorily showed QoL improvements of similar magnitude. Female gender was associated with a large, clinically relevant improvement in QoL at follow-up.

conclusionsIn-patient SUD treatment improved QoL at six month follow-up. These findings showed that QoL measurements were useful for providing evidence of therapeutic benefit in the SUD field.

Indexed as

Health StatusAdultFemaleFollow-Up StudiesHumansLongitudinal StudiesMaleMiddle AgedProspective StudiesQuality of LifeSex FactorsSubstance-Related DisordersSurveys and QuestionnairesTreatment Outcome

Identifiers

PMID25889576
PMCPMC4364507

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.