Evidence map›Paper›PMID 25889488›Full record

ReviewArthritis research & therapy2015

Parietal and intravascular innate mechanisms of vascular inflammation.

Giuseppe A Ramirez, Patrizia Rovere-Querini, Maria Grazia Sabbadini, Angelo A Manfredi

Open access · goldAbstract readReview
In one paragraph

Review in Arthritis research & therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Giuseppe A RamirezIRCCS Ospedale San Raffaele, via Olgettina 60, 20132, Milan, Italy. ramirez.giuseppealvise@hsr.it.
Patrizia Rovere-QueriniIRCCS Ospedale San Raffaele, via Olgettina 60, 20132, Milan, Italy. rovere.patrizia@hsr.it.
Maria Grazia SabbadiniIRCCS Ospedale San Raffaele, via Olgettina 60, 20132, Milan, Italy. sabbadini.mariagrazia@hsr.it.
Angelo A ManfrediIRCCS Ospedale San Raffaele, via Olgettina 60, 20132, Milan, Italy. manfredi.angelo@hsr.it.
Vita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sustained inflammation of the vessel walls occurs in a large number of systemic diseases (ranging from atherosclerosis to systemic vasculitides, thrombotic microangiopathies and connective tissue diseases), which are ultimately characterized by ischemia and end-organ failure. Cellular and humoral innate immunity contribute to a common pathogenic background and comprise several potential targets for therapeutic intervention. Here we discuss some recent advances in the effector and regulatory action of neutrophils and in the outcome of their interaction with circulating platelets. In parallel, we discuss novel insights into the role of humoral innate immunity in vascular inflammation. All these topics are discussed in light of potential clinical and therapeutic implications in the near future.

Indexed as

Blood PlateletsHumansImmunity, HumoralImmunity, InnateNeutrophilsVasculitis

Identifiers

PMID25889488
PMCPMC4308901
OpenAlexW2128124022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.