Evidence map›Paper›PMID 25889205›Full record

ArticleEnvironmental health : a global access science source2015

Ambient ozone exposure and children's acute asthma in New York City: a case-crossover analysis.

Perry Elizabeth Sheffield, Jiang Zhou, Jessie Loving Carr Shmool, Jane Ellen Clougherty

Open access · goldAbstract read
In one paragraph

Article in Environmental health : a global access science source, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 81 citations in OpenAlex.

  1. Article
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  5. Warm season ambient ozone and children's health in the USA.International journal of epidemiology · 2024
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  17. Social Susceptibility to Multiple Air Pollutants in Cardiovascular Disease.Research report (Health Effects Institute) · 2021
    Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Perry Elizabeth SheffieldIcahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl., Box 1057, DPM, New York, NY, 10029, USA. perry.sheffield@mssm.edu.
Jiang ZhouDepartment of Environmental and Occupational Health, University of Pittsburgh Graduate School of Public Health, 100 Technology Drive, Pittsburgh, PA, 15219, USA. jiz102@pitt.edu.
Jessie Loving Carr ShmoolDepartment of Environmental and Occupational Health, University of Pittsburgh Graduate School of Public Health, 100 Technology Drive, Pittsburgh, PA, 15219, USA. jlcshmool@pitt.edu.
Jane Ellen CloughertyDepartment of Environmental and Occupational Health, University of Pittsburgh Graduate School of Public Health, 100 Technology Drive, Pittsburgh, PA, 15219, USA. jcloughe@pitt.edu.
University of Pittsburgh · USIcahn School of Medicine at Mount Sinai · US

Funding

The Mount Sinai Transdisciplinary Center on Early Environmental ExposuresP30ES023515 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Maria Jose Rosa · 2014 to 2026
$21.3M
Prenatal Pollution, Stress and Maternal-child Health: Role of ImmunomodulationK23ES024127 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SHEFFIELD, PERRY ELIZABETH · 2014 to 2018
$832k
Children's Health and Vulnerability to Heat and Ozone in New York CityR21ES021429 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CLOUGHERTY, JANE ELLEN, SHEFFIELD, PERRY ELIZABETH · 2012 to 2013
$475k
NIEHS NIH HHS K23 ES024127NIEHS NIH HHS K23ES024127NIEHS NIH HHS L40 ES017745NIEHS NIH HHS P30 ES023515NIEHS NIH HHS R21 ES021429NIEHS NIH HHS R21ES021429
6 · The paper itself

Abstract

backgroundChildhood asthma morbidity has been associated with ambient ozone in case-crossover studies. Varying effects of ozone by child age and sex, however, have been less explored.

methodsThis study evaluates associations between ozone exposure and asthma emergency department visits and hospitalizations among boys and girls aged 5-17 years in New York City for the 2005-2011 warm season period. Time-stratified case-crossover analysis was conducted and, for comparison, time-series analysis controlling for season, day-of-week, same-day and delayed effects of temperature and relative humidity were also performed.

resultsWe found associations between ambient ozone levels and childhood asthma emergency department visits and hospitalizations in New York City, although the relationships varied among boys and girls and by age group. For an increase of interquartile range (0.013 ppm) in ozone, there was a 2.9-8.4% increased risk for boys and 5.4-6.5% for girls in asthma emergency department visits; and 8.2% increased risk for girls in hospitalizations. Among girls, we observed stronger associations among older children (10-13 and 14-17 year age groups). We did not observe significant modification by age for boys. Boys exhibited a more prompt response (lag day 1) to ozone than did girls (lag day 3), but significant associations for girls were retained longer, through lag day 6.

conclusionsOur study indicates significant variance in associations between short-term ozone concentrations and asthma events by child sex and age. Differences in ozone response for boys and girls, before and after puberty, may point towards both social (gendered) and biological (sex-linked) sources of effect modification.

Indexed as

Emergency Service, HospitalAcute DiseaseAdolescentAir PollutantsAsthmaChildChild, PreschoolCross-Over StudiesFemaleHumansMaleNew York CityOzoneRiskSeasonsAir PollutantsOzone

Identifiers

PMID25889205
PMCPMC4373115
OpenAlexW2149692031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.