ArticleBMC research notes2015
Positron emission tomography in the diagnosis of Whipple's endocarditis: a case report.
Article in BMC research notes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 11 citations in OpenAlex.
- Severe mitral valve papillary muscle rupture of isolated Whipple's endocarditis: a case report and review of the literature.Frontiers in cardiovascular medicine · 2025Article
- Prosthetic valve endocarditis secondary to Tropheryma whipplei in a patient with chronic polyarthritis.Journal of cardiothoracic surgery · 2023Article
- Could CT abdomen and PET/CT be helpful in early diagnosis of Whipple's disease? A case report.IDCases · 2021Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhipple's disease is a systemic infection that sometimes is associated with cardiac manifestations. The diagnosis of Tropheryma whipplei endocarditis is still the result of chance because there are no diagnostic criteria and clinical signs are often those of cardiac disease rather than infection. CASE PRESENTATION: Culture-negative endocarditis was suspected in a non-febrile 77-year-old French woman from North France with a history of a graft replacement 4 years prior. Positron emission tomography revealed intense fluorodeoxyglucose uptake around the metal ring of the aortic graft. The valve was replaced, and T. whipplei was detected in a valve sample by molecular assays. Immunohistochemical staining of the valve for T. whipplei was also positive.
conclusionThe localization of infectious foci by positron emission tomography and systematically testing valve specimens for T. whipplei are promising for diagnosing Whipple's disease.
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