ArticleMalaria journal2015
Modelling sterile insect technique to control the population of Anopheles gambiae.
Article in Malaria journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Agent-based models of malaria transmission: a systematic review.Malaria journal · 2018Pooled it
- Identifying Transgenic Approaches to Mitigate Vector Transmission of Malaria by Anopheles gambiae.Cureus · 2026Review
- Genetic Allee Effects for Controlling Invasive Populations.Molecular ecology · 2026Article
- Advancing Malaria Vector Control: Insights Into Mosquito Immunity and Genetic Strategies.TheScientificWorldJournal · 2026Review
- Improving the sex-specificity of a conditional female lethal system for genetic biocontrol of the New World screwworm, Cochliomyia hominivorax.Scientific reports · 2025Article
- How population control of pests is modulated by density dependence: The perspective of genetic biocontrol.Journal of theoretical biology · 2025Article
- Direct and transgenerational effects of tetracyclines on the microbiome, transcriptome, and male mating behavior of the sheep blowfly Lucilia cuprina.G3 (Bethesda, Md.) · 2025Article
- A Comparative Assessment of Self-limiting Genetic Control Strategies for Population Suppression.Molecular biology and evolution · 2025Article
- Article
- Unmanned aerial vehicles for surveillance and control of vectors of malaria and other vector-borne diseases.Malaria journal · 2023Review
- Gene drive designs for efficient and localisable population suppression using Y-linked editors.PLoS genetics · 2022Article
- Mathematical modeling of genetic pest management through female-specific lethality: Is one locus better than two?Evolutionary applications · 2021Article
- Comparing sterile male releases and other methods for integrated control of the tiger mosquito in temperate and tropical climates.Scientific reports · 2021Article
- The Sterile Insect Technique: Success and Perspectives in the Neotropics.Neotropical entomology · 2021Review
- Cartography of odor chemicals in the dengue vector mosquito (Aedes aegypti L., Diptera/Culicidae).Scientific reports · 2019Article
- The application of self-limiting transgenic insects in managing resistance in experimental metapopulations.The Journal of applied ecology · 2019Article
- Insect microbial symbionts as a novel source for biotechnology.World journal of microbiology & biotechnology · 2019Review
- Combining the high-dose/refuge strategy and self-limiting transgenic insects in resistance management-A test in experimental mesocosms.Evolutionary applications · 2018Article
- Larvicidal activity of Zanthoxylum acanthopodium essential oil against the malaria mosquitoes, Anopheles anthropophagus and Anopheles sinensis.Malaria journal · 2018Article
- Evidence for temporal population replacement and the signature of ecological adaptation in a major Neotropical malaria vector in Amazonian Peru.Malaria journal · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundThere is a renewed effort to develop novel malaria control strategies as even well-implemented existing malaria control tools may fail to block transmission in some regions. Currently, transgenic implementations of the sterile insect technique (SIT) such as the release of insects with a dominant lethal, homing endonuclease genes, or flightless mosquitoes are in development. These implementations involve the release of transgenic male mosquitoes whose matings with wild females produce either no viable offspring or no female offspring. As these technologies are all in their infancy, little is known about the relative efficiencies of the various implementations.
methodsThis paper describes agent-based modelling of emerging and theoretical implementations of transgenic SIT in Anopheles gambiae for the control of malaria. It reports on female suppression as it is affected by the SIT implementation, the number of released males, and competitiveness of released males.
conclusionsThe simulation experiments suggest that a late-acting bisex lethal gene is the most efficient of the four implementations we simulated. They demonstrate 1) the relative impact of release size on a campaign's effectiveness 2) late-acting genes are preferred because of their ability to exploit density dependent larval mortality 3) late-acting bisex lethal genes achieve elimination before their female-killing counterparts.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.