ReviewBMC medical ethics2015
Community engagement strategies for genomic studies in Africa: a review of the literature.
Review in BMC medical ethics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
89 citing papers in PubMed, 1 synthesis or guideline pooled it, 151 citations in OpenAlex.
- Advancing genetic counselling in Southern Africa: Unveiling opportunities for inclusive healthcare and genomic education for Angola.Saudi medical journal · 2025Pooled it
- Article
- Reciprocity and Narrative Agency in Index-Case Research: Ethical Reflections on Oropouche Vertical Transmission.Developing world bioethics · 2026Article
- Article
- When does broad consent expire? A temporal validity framework for biobank samples in induced pluripotent stem cell research.Research square · 2026Article
- Challenges and facilitators for meaningful and impactful stakeholder engagement in global health research.Journal of global health · 2026Article
- Willingness of adults to accept malaria mass drug administration using the theoretical framework of acceptability: a cross-sectional study in an urban municipality, Ghana.BMC public health · 2026Article
- Advocating for return-of-results to participants in microbiome research.Nature microbiology · 2026Article
- Participant engagement and feedback in microbiome projects: a case of AWI-Gen 2.bioRxiv : the preprint server for biology · 2026Article
- Return of health research findings in Nigeria-perspective of potential research participants.BMC medical ethics · 2026Article
- Integrating community engagement and involvement in surgical care processes in low-resource settings: a case study from Pakistan.Research involvement and engagement · 2026Article
- Strengthening research oversight in Ghana: a descriptive analysis of ethical and regulatory capacity gaps and opportunities.BMC medical ethics · 2026Article
- International expert perspectives on pharmacogenomics in pharmacy education: a qualitative study with implications for South Africa.Frontiers in pharmacology · 2026Article
- Engaging Communities and Empowering Research: Lessons from a Network of Community Engagement Cores.International journal of environmental research and public health · 2025Article
- Return of health research findings in Nigeria-perspective of potential research participants.Research square · 2025Article
- The role of community advisory boards in enhancing recruitment and retention in Alzheimer's disease and related dementia research in Africa: Experience from the READD-ADSP study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Research participants and stakeholders' views on feedback of genetic research findings: a qualitative study of the H3Africa Kidney Disease Research Network in Ghana.BMC nephrology · 2025Article
- Consideration and Disclosure of Group Risks in Genomics and Other Data-Centric Research: Does the Common Rule Need Revision?The American journal of bioethics : AJOB · 2025Article
- Respectful closure of a CEnR DNA integrity study: A bridge to sustained interactions with research participants.Journal of clinical and translational science · 2025Article
- Decolonisation and Self-Regulation as Alternative Paths to Data Science Health Research Governance in Africa.Wellcome open research · 2025Article
29 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 8 institutions in 6 countries.
Funding
Abstract
backgroundCommunity engagement has been recognised as an important aspect of the ethical conduct of biomedical research, especially when research is focused on ethnically or culturally distinct populations. While this is a generally accepted tenet of biomedical research, it is unclear what components are necessary for effective community engagement, particularly in the context of genomic research in Africa.
methodsWe conducted a review of the published literature to identify the community engagement strategies that can support the successful implementation of genomic studies in Africa. Our search strategy involved using online databases, Pubmed (National Library of Medicine), Medline and Google scholar. Search terms included a combination of the following: community engagement, community advisory boards, community consultation, community participation, effectiveness, genetic and genomic research, Africa, developing countries.
resultsA total of 44 articles and 1 thesis were retrieved of which 38 met the selection criteria. Of these, 21 were primary studies on community engagement, while the rest were secondary reports on community engagement efforts in biomedical research studies. 34 related to biomedical research generally, while 4 were specific to genetic and genomic research in Africa.
conclusionWe concluded that there were several community engagement strategies that could support genomic studies in Africa. While many of the strategies could support the early stages of a research project such as the recruitment of research participants, further research is needed to identify effective strategies to engage research participants and their communities beyond the participant recruitment stage. Research is also needed to address how the views of local communities should be incorporated into future uses of human biological samples. Finally, studies evaluating the impact of CE on genetic research are lacking. Systematic evaluation of CE strategies is essential to determine the most effective models of CE for genetic and genomic research conducted in African settings.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.