Evidence map›Paper›PMID 25888965›Full record

ArticleBMC veterinary research2015

Isolation of Leptospira interrogans serovar Hardjoprajitno from a calf with clinical leptospirosis in Chile.

Miguel Salgado, Barbara Otto, Manuel Moroni, Errol Sandoval, German Reinhardt, Sofia Boqvist, Carolina Encina, Claudia Muñoz-Zanzi

Abstract readCase Reports
In one paragraph

Article in BMC veterinary research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Serovar-specific genomic features ofFrontiers in molecular biosciences · 2025
    Article
  2. Investigation of Leptospirosis Agents in Cattle and Humans.The Malaysian journal of medical sciences : MJMS · 2024
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. PathogenicAnimals : an open access journal from MDPI · 2021
    Article
  9. Article
  10. Article
  11. Presence of Antibodies AgainstPolish journal of microbiology · 2019
    Article
  12. Article
  13. Culture Strategies for Isolation of FastidiousFrontiers in microbiology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Miguel SalgadoDepartment of Biochemistry and Microbiology, Faculty of Sciences, Universidad Austral de Chile, Edificio Instapanel, Campus Isla Teja, CC 567, Valdivia, Chile. miguelsalgado@uach.cl.
Barbara OttoDepartment of Biochemistry and Microbiology, Faculty of Sciences, Universidad Austral de Chile, Edificio Instapanel, Campus Isla Teja, CC 567, Valdivia, Chile. barbaraotto@uach.cl.
Manuel MoroniDepartment of Animal Pathology, Faculty of Veterinary Sciences, Universidad Austral de Chile, Valdivia, Chile. manuelmoroni@uach.cl.
Errol SandovalDepartment of Biochemistry and Microbiology, Faculty of Sciences, Universidad Austral de Chile, Edificio Instapanel, Campus Isla Teja, CC 567, Valdivia, Chile. errolsandoval@hotmail.com.
German ReinhardtDepartment of Biochemistry and Microbiology, Faculty of Sciences, Universidad Austral de Chile, Edificio Instapanel, Campus Isla Teja, CC 567, Valdivia, Chile. greinhar@uach.cl.
Sofia BoqvistDepartment of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, Box 7028, SE-750 07, Uppsala, Sweden. Sofia.Boqvist@slu.se.
Carolina EncinaDepartment of Biochemistry and Microbiology, Faculty of Sciences, Universidad Austral de Chile, Edificio Instapanel, Campus Isla Teja, CC 567, Valdivia, Chile. carolina.encina.o@gmail.com.
Claudia Muñoz-ZanziDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA. munozzan@umn.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough Leptospira isolation has been reported in Chilean cattle, only serological evidence of serovar Hardjo bovis infection has been routinely reported. The present report provides characterization of the pathological presentation and etiology of a clinical case of leptospirosis in a calf from the Los Rios Region in Chile. CASE PRESENTATION: In a dairy herd in southern Chile, 11 of 130 calves died after presenting signs such as depression and red-tinged urine. One of these calves, a female of eight months, was necropsied, and all the pathological findings were consistent with Leptospira infection. A urine sample was submitted to conventional bacteriological analysis together with highly specific molecular biology typing tools, in order to unravel the specific Leptospira specie and serovar associated with this clinical case. A significant finding of this study was that the obtained isolate was confirmed by PCR as L. interrogans, its VNTR profile properly matching with L. interrogans Hardjoprajitno as well as its specific genomic identity revealed by secY gen.

conclusionLeptospira interrogans serovar Hardjoprajitno was associated with the investigated calf clinical case. This information adds to the value of serologic results commonly reported, which encourage vaccination improvements to match circulating strains. In addition, this finding represents the first case report of this serovar in Chilean cattle.

Indexed as

AnimalsCattleCattle DiseasesChileFemaleLeptospira interrogansLeptospirosis

Identifiers

PMID25888965
PMCPMC4374366

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.