Evidence map›Paper›PMID 25888834›Full record

ArticleBiomedical engineering online2015

Automated system for lung nodules classification based on wavelet feature descriptor and support vector machine.

Hiram Madero Orozco, Osslan Osiris Vergara Villegas, Vianey Guadalupe Cruz Sánchez, Humberto de Jesús Ochoa Domínguez, Manuel de Jesús Nandayapa Alfaro

Abstract read
In one paragraph

Article in Biomedical engineering online, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  6. An anthropomorphic diagnosis system of pulmonary nodules using weak annotation-based deep learning.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hiram Madero OrozcoDepartamento de Ingeniería Industrial y Manufactura, Instituto de Ingeniería y Tecnología, Universidad Autónoma de Ciudad Juárez, Av. del Charro 450 norte, Z. C. 32310, Ciudad Juárez, Chihuahua, México. hrm.mad@gmail.com.
Osslan Osiris Vergara VillegasDepartamento de Ingeniería Industrial y Manufactura, Instituto de Ingeniería y Tecnología, Universidad Autónoma de Ciudad Juárez, Av. del Charro 450 norte, Z. C. 32310, Ciudad Juárez, Chihuahua, México. overgara@uacj.mx.
Vianey Guadalupe Cruz SánchezDepartamento de Ingeniería Eléctrica y Computación, Instituto de Ingeniería y Tecnología, Universidad Autónoma de Ciudad Juárez, Av. del Charro 450 norte, Z. C. 32310, Ciudad Juárez, Chihuahua, México. Vianey.cruz@uacj.mx.
Humberto de Jesús Ochoa DomínguezDepartamento de Ingeniería Eléctrica y Computación, Instituto de Ingeniería y Tecnología, Universidad Autónoma de Ciudad Juárez, Av. del Charro 450 norte, Z. C. 32310, Ciudad Juárez, Chihuahua, México. hochoa@uacj.mx.
Manuel de Jesús Nandayapa AlfaroDepartamento de Ingeniería Industrial y Manufactura, Instituto de Ingeniería y Tecnología, Universidad Autónoma de Ciudad Juárez, Av. del Charro 450 norte, Z. C. 32310, Ciudad Juárez, Chihuahua, México. mnandaya@uacj.mx.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLung cancer is a leading cause of death worldwide; it refers to the uncontrolled growth of abnormal cells in the lung. A computed tomography (CT) scan of the thorax is the most sensitive method for detecting cancerous lung nodules. A lung nodule is a round lesion which can be either non-cancerous or cancerous. In the CT, the lung cancer is observed as round white shadow nodules. The possibility to obtain a manually accurate interpretation from CT scans demands a big effort by the radiologist and might be a fatiguing process. Therefore, the design of a computer-aided diagnosis (CADx) system would be helpful as a second opinion tool.

methodsThe stages of the proposed CADx are: a supervised extraction of the region of interest to eliminate the shape differences among CT images. The Daubechies db1, db2, and db4 wavelet transforms are computed with one and two levels of decomposition. After that, 19 features are computed from each wavelet sub-band. Then, the sub-band and attribute selection is performed. As a result, 11 features are selected and combined in pairs as inputs to the support vector machine (SVM), which is used to distinguish CT images containing cancerous nodules from those not containing nodules.

resultsThe clinical data set used for experiments consists of 45 CT scans from ELCAP and LIDC. For the training stage 61 CT images were used (36 with cancerous lung nodules and 25 without lung nodules). The system performance was tested with 45 CT scans (23 CT scans with lung nodules and 22 without nodules), different from that used for training. The results obtained show that the methodology successfully classifies cancerous nodules with a diameter from 2 mm to 30 mm. The total preciseness obtained was 82%; the sensitivity was 90.90%, whereas the specificity was 73.91%.

conclusionsThe CADx system presented is competitive with other literature systems in terms of sensitivity. The system reduces the complexity of classification by not performing the typical segmentation stage of most CADx systems. Additionally, the novelty of the algorithm is the use of a wavelet feature descriptor.

Indexed as

Support Vector MachineWavelet AnalysisAlgorithmsArea Under CurveAutomationHumansImaging, Three-DimensionalIncidental FindingsLung NeoplasmsPattern Recognition, AutomatedRadiographic Image Interpretation, Computer-AssistedReferral and ConsultationROC CurveSensitivity and SpecificitySolitary Pulmonary NoduleTomography, X-Ray Computed

Identifiers

PMID25888834
PMCPMC4329222

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.