ArticleThe Plant cell2015
A Secreted Effector Protein of Ustilago maydis Guides Maize Leaf Cells to Form Tumors.
Article in The Plant cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.
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Who cites it
78 citing papers in PubMed, 158 citations in OpenAlex.
- The root-knot nematode effector Mi1D08B targets a NINJA-family co-repressor to suppress jasmonate production and promote infection in soybean.The Plant journal : for cell and molecular biology · 2026Article
- A multi-omics approach to maize (Zea mays) tassel development.BMC plant biology · 2026Article
- Host-Induced Silencing of Rhizoctonia Solani 5-Enolpyruvylshikimate-3-Phosphate Synthase Impairs Its Virulence in Rice.Plant biotechnology journal · 2026Article
- Pathogenic fungus Ustilago maydis exploits the lateral root regulators to induce pluripotency in maize shoots.The New phytologist · 2026Article
- Wheat Germ Agglutinin-Alexa Fuor488/Propidium Iodine Costaining and Fluorescence Microscopic Imaging of Ustilago maydis Infected Maize Anthers.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Ustilago maydis Seedling Infection Assay and Scoring.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Structural and Functional Analysis of the Lectin-like Protein Llp1 Secreted byJournal of fungi (Basel, Switzerland) · 2025Article
- Adaptation ofFrontiers in plant science · 2024Article
- The response of rhubarb to smut infection is revealed through a comparative transcriptome and metabolome study.Planta · 2023Article
- Manipulation of Auxin Signaling by Smut Fungi during Plant Colonization.Journal of fungi (Basel, Switzerland) · 2023Review
- A transcriptional activator effector of Ustilago maydis regulates hyperplasia in maize during pathogen-induced tumor formation.Nature communications · 2023Article
- Combination of in vivo proximity labeling and co-immunoprecipitation identifies the host target network of a tumor-inducing effector in the fungal maize pathogen Ustilago maydis.Journal of experimental botany · 2023Article
- The neighbouring genes AvrLm10A and AvrLm10B are part of a large multigene family of cooperating effector genes conserved in Dothideomycetes and Sordariomycetes.Molecular plant pathology · 2023Article
- Special issue: Genetics of maize-microbe interactions.Molecular plant pathology · 2023Article
- Nuclear effectors of plant pathogens: Distinct strategies to be one step ahead.Molecular plant pathology · 2023Review
- Genomic Assessment of the Contribution of theInternational journal of molecular sciences · 2023Article
- The nuclear effector MoHTR3 of Magnaporthe oryzae modulates host defence signalling in the biotrophic stage of rice infection.Molecular plant pathology · 2023Article
- Progress in pathogenesis research of Ustilago maydis, and the metabolites involved along with their biosynthesis.Molecular plant pathology · 2023Review
- Article
- Germicide Fenaminosulf Promots Gall Formation of Zizania latifolia without directly affecting the growth of endophytic fungus Ustilago esculenta.BMC plant biology · 2022Article
18 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The biotrophic smut fungus Ustilago maydis infects all aerial organs of maize (Zea mays) and induces tumors in the plant tissues. U. maydis deploys many effector proteins to manipulate its host. Previously, deletion analysis demonstrated that several effectors have important functions in inducing tumor expansion specifically in maize leaves. Here, we present the functional characterization of the effector See1 (Seedling efficient effector1). See1 is required for the reactivation of plant DNA synthesis, which is crucial for tumor progression in leaf cells. By contrast, See1 does not affect tumor formation in immature tassel floral tissues, where maize cell proliferation occurs independent of fungal infection. See1 interacts with a maize homolog of SGT1 (Suppressor of G2 allele of skp1), a factor acting in cell cycle progression in yeast (Saccharomyces cerevisiae) and an important component of plant and human innate immunity. See1 interferes with the MAPK-triggered phosphorylation of maize SGT1 at a monocot-specific phosphorylation site. We propose that See1 interferes with SGT1 activity, resulting in both modulation of immune responses and reactivation of DNA synthesis in leaf cells. This identifies See1 as a fungal effector that directly and specifically contributes to the formation of leaf tumors in maize.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.