Evidence map›Paper›PMID 25888327›Full record

ArticleBMC oral health2015

Oral findings in chronic kidney disease: implications for management in developing countries.

Elijah O Oyetola, Foluso J Owotade, Gbemisola A Agbelusi, Olawumi A Fatusi, Abubarkar A Sanusi

Registry-linked trialOpen access · goldAbstract readComparative Study
In one paragraph

Article in BMC oral health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06077188 (Erciyes University), which is not on this map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06077188 nacompletednot on this mapstarted 2024, after this paper: background citation

Erciyes University

TypeinterventionalSponsorTC Erciyes UniversityRan2024 to 2024Enrolled60ConditionsAcute Pancreatitis, ThirstArmsGum group
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 100 citations in OpenAlex.

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  17. Effect of Chronic Kidney Disease on Taste Function: A Case Control Study among Nigerian.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Elijah O OyetolaDepartment of Preventive and Community Dentistry, Obafemi Awolowo University Teaching Hospitals Complex, Ile Ife, Osun State, Nigeria. Phemyhoye12@yahoo.com.
Foluso J OwotadeDepartment of Oral and Maxillofacial Surgery and Oral Pathology, Obafemi Awolowo University Teaching Hospitals Complex, Ile Ife, Osun State, Nigeria. folu_owotade@yahoo.com.
Gbemisola A AgbelusiDepartment of Preventive Dentistry, Lagos University Teaching Hospital, Idi- Araba, Lagos State, Nigeria. gbemisola4life2004@yahoo.com.
Olawumi A FatusiDepartment of Oral and Maxillofacial Surgery and Oral Pathology, Obafemi Awolowo University Teaching Hospitals Complex, Ile Ife, Osun State, Nigeria. ofatusi@yahoo.com.
Abubarkar A SanusiDepartment of Internal Medicine, Obafemi Awolowo University Teaching Hospitals Complex, Ile Ife, Osun State, Nigeria. abubakrabefe@yahoo.com.
Obafemi Awolowo University Teaching Hospitals Complex · NGLagos University Teaching Hospital · NGObafemi Awolowo University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe importance of oral health care in the management of patients with systemic diseases including chronic kidney disease (CKD) has been affirmed. Many CKD patients have related oral lesions, however, attention to oral health care has been lacking, especially in the developing countries with higher burden of renal diseases.

methodsOne hundred and eighty patients, 90 cases and 90 controls were recruited, interviewed and examined. Oral mucosa assessment was based on the WHO Guide to Epidemiology and Diagnosis of Oral Mucosal Diseases. Urinalysis and blood creatinine levels were determined. Glomerular filtration rate (GFR) of each patient was calculated from the blood creatinine using Cockcroft and Gault formula.

resultsOral lesions were present in 86 out of 90 (96.5%) CKD patients compared with 15 out of 90 (16.7%) controls (p < 0.001). Abnormal lip hyperpigmentation was the most frequently seen lesion in 81 out of 90 (90%) CKD patients. Other significant findings were gum bleeding, xerostomia, candidiasis, burning mouth and abnormal taste. In the controls (without CKD), the mean GFR was lower in subjects with oral lesions compared with those without oral lesions p < 0.001.

conclusionsCKD and reduced GFR in subjects without CKD are risk factors for oral lesions. The higher prevalence of oral lesions in CKD patients necessitates mandatory oral screening to identify patients with deteriorating renal function. The management of such lesions will enhance the overall well-being of CKD patients in developing countries.

Indexed as

Developing CountriesAdultAgedBurning Mouth SyndromeCandidiasis, OralCase-Control StudiesCreatinineFemaleGingival HemorrhageGlomerular Filtration RateHumansHyperpigmentationKidney Failure, ChronicLip DiseasesMaleMiddle AgedCreatinine

Identifiers

PMID25888327
PMCPMC4350651
OpenAlexW2066055445

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.