Evidence map›Paper›PMID 25887980›Full record

ReviewThe Lancet. Respiratory medicine2015

On the cutting edge of obstructive sleep apnoea: where next?

Atul Malhotra, Jeremy E Orr, Robert L Owens

3 registry-linked trialsAbstract readReview
In one paragraph

Review in The Lancet. Respiratory medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02566278 naterminatednot on this map

Determination of Upper Airway Collapsibility During Routine CPAP Titration

TypeinterventionalSponsorUniversity of California, San DiegoRan2015 to 2016Enrolled20ConditionsObstructive Sleep ApneaArmsUpper airway collapsibility (Pcrit)
NCT04021810 naterminatednot on this mapstarted 2019, after this paper: background citation

Combination Therapy Associating CPAP and Mandibular Advancement Device ( MAD) in Obstructive Sleep Apnea (OSA) Low CPAP Compliers: A Randomized Controlled Trial

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2019 to 2021Enrolled5ConditionsObstructive Sleep Apnea Syndrome, HypertensionArmsContinuous Positive Airway Pressure (CPAP) and patient education, Mandibular Advancement Device
NCT04054180 naterminatednot on this mapstarted 2021, after this paper: background citation

Multimodal Remote Monitoring and Integrated Educational Program in OSA Patients Initiating Continuous Positive Airway Pressure (CPAP): a Prospective Intervention (SLEEPCONNECT)

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2021 to 2024Enrolled41ConditionsObstructive Sleep Apnea SyndromeArmsCPAP associated with connected devices: blood pressure monitor , scales and activity monitor
3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Racial and Ethnic Disparities in the Diagnosis and Treatment of Obstructive Sleep Apnea: A Systematic Review.International journal of environmental research and public health · 2026
    Pooled it
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  14. Monitoring Seasonal Compliance of Patients with Obstructive Sleep Apnea Using CPAP Systems via SD Card.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Atul MalhotraPulmonary, Critical Care, and Sleep Medicine Division, University of California San Diego, La Jolla, CA, USA. Electronic address: amalhotra@ucsd.edu.
Jeremy E OrrPulmonary, Critical Care, and Sleep Medicine Division, University of California San Diego, La Jolla, CA, USA.
Robert L OwensPulmonary, Critical Care, and Sleep Medicine Division, University of California San Diego, La Jolla, CA, USA.

Funding

Single Motor Unit Genioglossus Recordings to Understand Sleep Apnea PathogenesisR01HL085188 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2008 to 2018
$3.5M
Assessment of Upper Airway Mechanics Using Newer EMG TechniquesK24HL093218 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2009 to 2013
$857k
NHLBI NIH HHS K24 HL093218NHLBI NIH HHS R01 HL085188
6 · The paper itself

Abstract

Obstructive sleep apnoea is a common disease that is now more widely recognised because of the rise in prevalence and the increasingly compelling data that shows major neurocognitive and cardiovascular sequelae. At the same time, the clinical practice of sleep medicine is changing rapidly, with novel diagnostics and treatments that have established a home-based (rather than laboratory-based) management approach. We review the most recent insights and discoveries in obstructive sleep apnoea, with a focus on diagnostics and therapeutics. As will be discussed, management of obstructive sleep apnoea could soon transition from a so-called one size fits all approach to an individualised approach.

Indexed as

Continuous Positive Airway PressureHumansPolysomnographyRisk FactorsSleep Apnea, Obstructive

Identifiers

PMID25887980
PMCPMC4431916

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.