ArticleBMC genomics2015
Divergences in gene repertoire among the reference Prevotella genomes derived from distinct body sites of human.
Article in BMC genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 55 citations in OpenAlex.
- Trial
- Review
- The redefined identity ofJournal of bacteriology · 2026Review
- Physiology and comparative genomics of the haloalkalitolerant and hydrocarbonoclastic marine strain Rhodococcus ruber MSA14.Archives of microbiology · 2024Article
- The Contribution of the Human Oral Microbiome to Oral Disease: A Review.Microorganisms · 2023Review
- Genomic Insights into the Distribution of Peptidases and Proteolytic Capacity amongMicrobiology spectrum · 2022Article
- Microbiome and metabolome profiles of high screen time in a cohort of healthy college students.Scientific reports · 2022Article
- Analysis of the fecal and oral microbiota in chronic recurrent multifocal osteomyelitis.Arthritis research & therapy · 2022Article
- Genomic diversity and antimicrobial resistance ofMicrobial genomics · 2022Article
- Article
- Prevotella diversity, niches and interactions with the human host.Nature reviews. Microbiology · 2021Review
- Cultivation of the gut bacterium Prevotella copri DSM 18205MicrobiologyOpen · 2021Article
- Development of a real-time quantitative PCR method for detection and quantification of Prevotella copri.BMC microbiology · 2021Article
- 16S rDNA Full-Length Assembly Sequencing Technology Analysis of Intestinal Microbiome in Polycystic Ovary Syndrome.Frontiers in cellular and infection microbiology · 2021Article
- Perturbation of the gut microbiome by Prevotella spp. enhances host susceptibility to mucosal inflammation.Mucosal immunology · 2021Article
- Discovery of Predictors ofMicroorganisms · 2020Article
- Complete, closed bacterial genomes from microbiomes using nanopore sequencing.Nature biotechnology · 2020Article
- Defining microbial biomarkers for risk of preterm labor.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020Article
- Article
- Comparative Genomics of RumenApplied and environmental microbiology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe community composition of the human microbiome is known to vary at distinct anatomical niches. But little is known about the nature of variations, if any, at the genome/sub-genome levels of a specific microbial community across different niches. The present report aims to explore, as a case study, the variations in gene repertoire of 28 Prevotella reference genomes derived from different body-sites of human, as reported earlier by the Human Microbiome Consortium.
resultsThe pan-genome for Prevotella remains "open". On an average, 17% of predicted protein-coding genes of any particular Prevotella genome represent the conserved core genes, while the remaining 83% contribute to the flexible and singletons. The study reveals exclusive presence of 11798, 3673, 3348 and 934 gene families and exclusive absence of 17, 221, 115 and 645 gene families in Prevotella genomes derived from human oral cavity, gastro-intestinal tracts (GIT), urogenital tract (UGT) and skin, respectively. Distribution of various functional COG categories differs significantly among the habitat-specific genes. No niche-specific variations could be observed in distribution of KEGG pathways.
conclusionsPrevotella genomes derived from different body sites differ appreciably in gene repertoire, suggesting that these microbiome components might have developed distinct genetic strategies for niche adaptation within the host. Each individual microbe might also have a component of its own genetic machinery for host adaptation, as appeared from the huge number of singletons.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.