Evidence map›Paper›PMID 25887900›Full record

ReviewCurrent opinion in nephrology and hypertension2015

Body composition in chronic kidney disease.

Kirsten L Johansen, Carol Lee

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in nephrology and hypertension, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 98 citations in OpenAlex.

  1. Trial
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  6. The Role of Precision Nutrition in Kidney Disease.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Review
  7. Body roundness index and mortality risk in patients with chronic kidney disease: moving beyond the obesity paradox.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kirsten L JohansenDivision of Nephrology, University of California, San Francisco, California, USA.
Carol Lee
University of California, San Francisco · US

Funding

Prevalence and Impact of Frailty among Dialysis PatientsK24DK085153 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHANSEN, KIRSTEN L. · 2010 to 2021
$1.5M
NIDDK NIH HHS DK085153NIDDK NIH HHS K24 DK085153
6 · The paper itself

Abstract

purpose of reviewTo summarize the latest information on body composition among patients with chronic kidney disease and its association with outcomes. RECENT

findingsObesity is increasing among patients with end-stage renal disease and is more prevalent when direct measures of adiposity are used rather than BMI. High BMI is not associated with better survival among patients with earlier chronic kidney disease or after kidney transplantation, suggesting that excess fat is most protective among the sickest patients. Despite the positive association between BMI and survival among patients with end-stage renal disease, visceral fat is associated with coronary artery calcification and adverse cardiovascular events. Muscle wasting is prominent among patients with chronic kidney disease, sometimes even in the setting of obesity. Obesity and muscle wasting are associated with worse physical functioning. Indicators of low muscle size and strength are associated with higher mortality. Some interventions can affect body composition, but whether they affect survival has not been determined. SUMMARY: Recent studies show that a high BMI is not protective for all patients with chronic kidney disease and is associated with poor physical functioning and frailty. Visceral adiposity is associated with adverse cardiovascular outcomes. Sarcopenia is common among patients with end-stage renal disease and is associated with worse physical performance and higher mortality.

Indexed as

AdiposityBody CompositionBody Mass IndexHumansObesityRenal DialysisRenal Insufficiency, Chronic

Identifiers

PMID25887900
PMCPMC4778545
OpenAlexW2325594752

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.