ArticleBMC genomics2015
Genome reduction and potential metabolic complementation of the dual endosymbionts in the whitefly Bemisia tabaci.
Article in BMC genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
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Who cites it
58 citing papers in PubMed, 123 citations in OpenAlex.
- Genomic and metabolic divergence of the primary symbiont Candidatus Portiera between Bemisia tabaci and other whitefly species.BMC genomics · 2026Article
- Comparative genomics and metabolic model analysis of primary and secondary endosymbionts present in different species of whitefly.Journal of insect science (Online) · 2026Article
- Magnetoreception in a freshwater ciliate arises from endosymbiosis.Nature communications · 2026Article
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- PacBio Hi-Fi genome assembly of Sipha maydis, a model for the study of multipartite mutualism in insects.Scientific data · 2024Article
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- The Susceptibility ofInsects · 2023Article
- Subcellular Niche Segregation of Co-Obligate Symbionts in Whiteflies.Microbiology spectrum · 2023Article
- Complex host/symbiont integration of a multi-partner symbiotic system in the eusocial aphidiScience · 2022Article
- Analysis of the Type 4 Effectome across the GenusInternational journal of molecular sciences · 2022Article
- Spatial distribution and community structure of microbiota associated with cowpea aphid (3 Biotech · 2022Article
- Transitional genomes and nutritional role reversals identified for dual symbionts of adelgids (Aphidoidea: Adelgidae).The ISME journal · 2022Article
- Whitefly endosymbionts: IPM opportunity or tilting at windmills?Journal of pest science · 2022Review
- Spatio-temporal changes in endosymbiont diversity and composition in the African cassava whitefly,Frontiers in microbiology · 2022Article
- Article
- Evolutionary genomics of APSE: a tailed phage that lysogenically converts the bacterium Hamiltonella defensa into a heritable protective symbiont of aphids.Virology journal · 2021Article
- Genome Reduction Is Associated with Bacterial Pathogenicity across Different Scales of Temporal and Ecological Divergence.Molecular biology and evolution · 2021Article
Corrections and comments
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Authors and funding
13 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe whitefly Bemisia tabaci is an important agricultural pest with global distribution. This phloem-sap feeder harbors a primary symbiont, "Candidatus Portiera aleyrodidarum", which compensates for the deficient nutritional composition of its food sources, and a variety of secondary symbionts. Interestingly, all of these secondary symbionts are found in co-localization with the primary symbiont within the same bacteriocytes, which should favor the evolution of strong interactions between symbionts.
resultsIn this paper, we analyzed the genome sequences of the primary symbiont Portiera and of the secondary symbiont Hamiltonella in the B. tabaci Mediterranean (MED) species in order to gain insight into the metabolic role of each symbiont in the biology of their host. The genome sequences of the uncultured symbionts Portiera and Hamiltonella were obtained from one single bacteriocyte of MED B. tabaci. As already reported, the genome of Portiera is highly reduced (357 kb), but has kept a number of genes encoding most essential amino-acids and carotenoids. On the other hand, Portiera lacks almost all the genes involved in the synthesis of vitamins and cofactors. Moreover, some pathways are incomplete, notably those involved in the synthesis of some essential amino-acids. Interestingly, the genome of Hamiltonella revealed that this secondary symbiont can not only provide vitamins and cofactors, but also complete the missing steps of some of the pathways of Portiera. In addition, some critical amino-acid biosynthetic genes are missing in the two symbiotic genomes, but analysis of whitefly transcriptome suggests that the missing steps may be performed by the whitefly itself or its microbiota.
conclusionsThese data suggest that Portiera and Hamiltonella are not only complementary but could also be mutually dependent to provide a full complement of nutrients to their host. Altogether, these results illustrate how functional redundancies can lead to gene losses in the genomes of the different symbiotic partners, reinforcing their inter-dependency.
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