ArticleBMC endocrine disorders2015
A rare case of anasarca caused by infiltration of the pituitary gland by diffuse large B-cell lymphoma.
Article in BMC endocrine disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 5 citations in OpenAlex.
- A sellar mass as the initial presentation of pituitary infiltration by diffuse large B-cell lymphoma: a case report.Frontiers in oncology · 2026Article
- Pituitary Infiltration by Lymphoma.Journal of the Endocrine Society · 2022Article
- Diffuse large B cell lymphoma with bilateral adrenal and hypothalamic involvement: A case report and literature review.World journal of clinical cases · 2019Article
- Infundibulo-hypophysitis-like radiological image in a patient with pituitary infiltration of a diffuse large B-cell non-Hodgkin lymphoma.Endocrinology, diabetes & metabolism case reports · 2016Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
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Abstract
backgroundAnasarca in patients with lymphoma is a rare symptom. We report a patient with DLBCL associated with pituitary gland infiltration that was diagnosed based on significant anasarca. CASE PRESENTATION: A 72-year-old woman with a 10-year history of hypertension visited a local hospital presenting with anasarca and 15-kg weight gain in the past 3 months. we clinically diagnosed central hypothyroidism caused by pituitary gland infiltration of diffuse large B-cell lymphoma (DLBCL) (clinical stage IV in the Ann Arbor staging classification). The first course of chemotherapy improved anasarca remarkably and the patient's body weight returned to what it was 3 months before.
conclusionsWe experienced a patient with remarkable anasarca caused by DLBCL infiltration of the pituitary gland. A pituitary gland lesion with central hypothyroidism should be considered as one of the differential diagnoses of edema. This case was very valuable because we could assess it by following the time course of symptoms (edema and delayed relaxation time of the Achilles tendon reflex), laboratory data, and imaging findings (swelling anterior pituitary lobe).
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