ReviewCurrent opinion in infectious diseases2015
Rational development of guidelines for management of neonatal sepsis in developing countries.
Review in Current opinion in infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Antibiotic regimens for early-onset neonatal sepsis.The Cochrane database of systematic reviews · 2021Pooled it
- Antibiotic regimens for late-onset neonatal sepsis.The Cochrane database of systematic reviews · 2021Pooled it
- Task-shifting and system readiness: a narrative review of strategies for pediatric emergency care in low-resource settings.International journal of emergency medicine · 2025Review
- Metagenomic profiles of the early life microbiome of Indonesian inpatient neonates and their influence on clinical characteristics.Scientific reports · 2022Article
- Early-onset neonatal sepsis and antibiotic use in Indonesia: a descriptive, cross-sectional study.BMC public health · 2022Article
- Clinical and laboratory factors associated with neonatal sepsis mortality at a major Vietnamese children's hospital.PLOS global public health · 2022Article
- Bacteria profiles and risk factors for proven early-onset sepsis in preterm neonates.Saudi medical journal · 2021Article
- Risk factors and clinical analysis of peripherally inserted central catheter-related fungal colonization in premature infants.Scientific reports · 2021Article
- Assessing the impact of the Global Point Prevalence Survey of Antimicrobial Consumption and Resistance (Global-PPS) on hospital antimicrobial stewardship programmes: results of a worldwide survey.Antimicrobial resistance and infection control · 2021Article
- Clinical Profile of Neonates Admitted with Sepsis to Neonatal Intensive Care Unit of Jimma Medical Center, A Tertiary Hospital in Ethiopia.Ethiopian journal of health sciences · 2021Article
- Simplified Dosing Regimens for Gentamicin in Neonatal Sepsis.Frontiers in pharmacology · 2021Article
- Risk factors for mortality among neonates admitted to a special care unit in a low-resource setting.BMC pregnancy and childbirth · 2020Observational
- Antibiotic regimens for neonatal sepsis - a protocol for a systematic review with meta-analysis.Systematic reviews · 2019Article
- Population-based study of early-onset neonatal sepsis in Canada.Paediatrics & child health · 2019Article
- In search of a primary outcome for community-based newborn infection trials in Eastern Uganda: a nested cohort study within the BabyGel pilot trial.Pilot and feasibility studies · 2019Article
- Ceftriaxone Absorption Enhancement for Noninvasive Administration as an Alternative to Injectable Solutions.Antimicrobial agents and chemotherapy · 2018Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
purpose of reviewThis review discusses the rational development of guidelines for the management of neonatal sepsis in developing countries. RECENT
findingsDiagnosis of neonatal sepsis with high specificity remains challenging in developing countries. Aetiology data, particularly from rural, community-based studies, are very limited, but molecular tests to improve diagnostics are being tested in a community-based study in South Asia. Antibiotic susceptibility data are limited, but suggest reducing susceptibility to first-and second-line antibiotics in both hospital and community-acquired neonatal sepsis. Results of clinical trials in South Asia and sub-Saharan Africa assessing feasibility of simplified antibiotic regimens are awaited. SUMMARY: Effective management of neonatal sepsis in developing countries is essential to reduce neonatal mortality and morbidity. Simplified antibiotic regimens are currently being examined in clinical trials, but reduced antimicrobial susceptibility threatens current empiric treatment strategies. Improved clinical and microbiological surveillance is essential, to inform current practice, treatment guidelines, and monitor implementation of policy changes.
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