Trial reportBMC musculoskeletal disorders2015
Outcome prediction in chronic unilateral lumbar radiculopathy: prospective cohort study.
Trial report in BMC musculoskeletal disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Using Inflammatory Biomarkers and EMG Results to Predict Epidural Injection Response in Patients Diagnosed With Lumbar Stenosis
Comparative Effects Of High Intensity Spinal Decompression Exercises And Eldoa On Pain, Range Of Motion And Disability In Patients Of Lumbar Radiculopathy
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Management of low back pain and lumbosacral radicular syndrome: the Guideline of the Royal Dutch Society for Physical Therapy (KNGF).European journal of physical and rehabilitation medicine · 2024Guideline
- Effects of non-surgical decompression therapy in addition to routine physical therapy on pain, range of motion, endurance, functional disability and quality of life versus routine physical therapy alone in patients with lumbar radiculopathy; a randomized controlled trial.BMC musculoskeletal disorders · 2022Trial
- Stratified versus usual care for the management of primary care patients with sciatica: the SCOPiC RCT.Health technology assessment (Winchester, England) · 2020Trial
- Fear avoidance beliefs as a predictor for long-term sick leave, disability and pain in patients with chronic low back pain.BMC musculoskeletal disorders · 2018Trial
- Social factors contributing to the development of chronic low back pain: a scoping review.BMC musculoskeletal disorders · 2025Article
- Article
- Importance of serum albumin in machine learning-based prediction of cognitive function in the elderly using a basic blood test.Frontiers in neurology · 2024Article
- Article
- Does a Positive Response to Transforaminal Epidural Steroid Injection Identify Patients Who Can Avoid Surgery for Two Years?Pain research & management · 2023Observational
- ACUTE RADIATING LOW BACK PAIN IMPACT ON ROUTINE AND FUNCTION OF THE BRAZILIAN POPULATION: A CROSS-SECTIONAL STUDY.Acta ortopedica brasileira · 2023Article
- Strength Back - A qualitative study on the co-creation of a positive psychology digital health intervention for spinal surgery patients.Frontiers in psychology · 2023Article
- [Entrapment neuropathies: a contemporary approach to pathophysiology, clinical assessment, and management : German version].Schmerz (Berlin, Germany) · 2021Review
- Article
- Falling risk in patients with end-stage knee osteoarthritis.Clinical rheumatology · 2021Review
- AAAPT Diagnostic Criteria for Acute Low Back Pain with and Without Lower Extremity Pain.Pain medicine (Malden, Mass.) · 2020Review
- Prognosis of sciatica and back-related leg pain in primary care: the ATLAS cohort.The spine journal : official journal of the North American Spine Society · 2018Article
- Review
- Entrapment neuropathies: a contemporary approach to pathophysiology, clinical assessment, and management.Pain reportsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIdentification of prognostic factors for persistent pain and disability are important for better understanding of the clinical course of chronic unilateral lumbar radiculopathy and to assist clinical decision-making. There is a lack of scientific evidence concerning prognostic factors. The aim of this study was to identify clinically relevant predictors for outcome at 52 weeks.
methods116 patients were included in a sham controlled clinical trial on epidural injection of glucocorticoids in patients with chronic unilateral lumbar radiculopathy. Success at follow-up was ≤ 17.5 for visual analogue scale (VAS) leg pain, ≤ 22.5 for VAS back pain and ≤ 20 for Oswestry Disability Index (ODI). Fifteen clinically relevant variables included demographic, psychosocial, clinical and radiological data and were analysed using a logistic multivariable regression analysis.
resultsAt follow-up, 75 (64.7%) patients had reached a successful outcome with an ODI score ≤ 20, 54 (46.6%) with a VAS leg pain score ≤ 17.5, and 47 (40.5%) with a VAS back pain score ≤ 22.5. Lower age (OR 0.94 (CI 0.89-0.99) for each year decrease in age) and FABQ Work ≥ 34 (OR 0.16 (CI 0.04-0.61)) were independent variables predicting a successful outcome on the ODI. Higher education (OR 5.77 (CI 1.46-22.87)) and working full-time (OR 2.70 (CI 1.02-7.18)) were statistically significant (P <0.05) independent predictors for successful outcome (VAS score ≤ 17.5) on the measure of leg pain. Lower age predicted success on ODI (OR 0.94 (95% CI 0.89 to 0.99) for each year) and less back pain (OR 0.94 (0.90 to 0.99)), while higher education (OR 5.77 (1.46 to 22.87)), working full-time (OR 2.70 (1.02 to 7.18)) and muscle weakness at baseline (OR 4.11 (1.24 to 13.61) predicted less leg pain, and reflex impairment at baseline predicted the contrary (OR 0.39 (0.15 to 0.97)).
conclusionsLower age, higher education, working full-time and low fear avoidance beliefs each predict a better outcome of chronic unilateral lumbar radiculopathy. Specifically, lower age and low fear avoidance predict a better functional outcome and less back pain, while higher education and working full-time predict less leg pain. These results should be validated in further studies before being used to inform patients.
trial registrationCurrent Controlled Trials ISRCTN12574253 . Registered 18 May 2005.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.