Evidence map›Paper›PMID 25887412›Full record

ArticleBMC genomics2015

GRACOMICS: software for graphical comparison of multiple results with omics data.

Minseok Seo, Joon Yoon, Taesung Park

Abstract read
In one paragraph

Article in BMC genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Characterizing Milk Production Related Genes in Holstein Using RNA-seq.Asian-Australasian journal of animal sciences · 2016
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Minseok SeoInterdiciplinary of Bioinformatics Program, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, Korea. nijorral@gmail.com.
Joon YoonInterdiciplinary of Bioinformatics Program, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, Korea. joonyoon.jay@gmail.com.
Taesung ParkInterdiciplinary of Bioinformatics Program, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, Korea. tspark@stats.snu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnalysis of large-scale omics data has become more and more challenging due to high dimensionality. More complex analysis methods and tools are required to handle such data. While many methods already exist, those methods often produce different results. To help users obtain more appropriate results (i.e. candidate genes), we propose a tool, GRACOMICS that compares numerous analysis results visually in a more systematic way; this enables the users to easily interpret the results more comfortably.

resultsGRACOMICS has the ability to visualize multiple analysis results interactively. We developed GRACOMICS to provide instantaneous results (plots and tables), corresponding to user-defined threshold values, since there are yet no other up-to-date omics data visualization tools that provide such features. In our analysis, we successfully employed two types of omics data: transcriptomic data (microarray and RNA-seq data) and genomic data (SNP chip and NGS data).

conclusionsGRACOMICS is a graphical user interface (GUI)-based program written in Java for cross-platform computing environments, and can be applied to compare analysis results for any type of large-scale omics data. This tool can be useful for biologists to identify genes commonly found by intersected statistical methods, for further experimental validation.

Indexed as

Computer GraphicsSoftwareElectronic Data ProcessingHigh-Throughput Nucleotide SequencingOligonucleotide Array Sequence AnalysisPolymorphism, Single NucleotideSequence Analysis, RNA

Identifiers

PMID25887412
PMCPMC4387734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.