ArticleCritical care (London, England)2015
Acute kidney injury after cardiac arrest.
Article in Critical care (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
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Who cites it
66 citing papers in PubMed, 138 citations in OpenAlex.
- Pharmacokinetics of Loading Dose Vigabatrin Administered via Enteral Tube in Participants With Post-Anoxic Status Epilepticus.Pharmacotherapy · 2026Trial
- Acute kidney injury after in-hospital cardiac arrest.Resuscitation · 2021Trial
- Factors associated with good neurological outcomes in survivors of in-hospital cardiac arrest: A systematic review and meta-analysis.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2026Review
- Association between C-reactive protein-to-platelet ratio and acute kidney injury in cardiac arrest survivors.BMC cardiovascular disorders · 2026Article
- Protective Effects of Selective β-Adrenoceptor Blockade on Renal Pathophysiology in a Catecholamine Storm of Rat.International journal of molecular sciences · 2026Article
- Dual-phase CT radiomics for acute kidney injury prediction after out-of-hospital cardiac arrest.Frontiers in radiology · 2026Article
- Integrated transcriptomics identifies ER stress-associated apoptosis in post-resuscitation AKI and supports early Dl-3-n-butylphthalide-associated renoprotection in a porcine TCA model.Frontiers in pharmacology · 2026Article
- Proteomics identify pathogenesis and novel biomarkers for monitoring and early prognostication of brain injury after cardiac arrest: a randomized animal study.Resuscitation plus · 2025Article
- Serum alkaline phosphatase levels and their association with neurological outcomes post-cardiac arrest.BMC cardiovascular disorders · 2025Article
- Kidney cell response to acute cardiorenal and isolated kidney ischemia-reperfusion injury.Physiological genomics · 2025Article
- Causes and Clinical Outcomes of Acute Kidney Injury After Cardiac Arrest: A Retrospective Cohort Study.Medicina (Kaunas, Lithuania) · 2025Article
- Acute Kidney Injury in Patients After Cardiac Arrest: Effects of Targeted Temperature Management.Life (Basel, Switzerland) · 2025Article
- Development and validation of a prediction model of hospital mortality for patients with cardiac arrest survived 24 hours after cardiopulmonary resuscitation.Frontiers in cardiovascular medicine · 2025Article
- Association between serum alkaline phosphatase and clinical prognosis in patients with acute liver failure following cardiac arrest: a retrospective cohort study.European journal of medical research · 2024Article
- Extracerebral multiple organ dysfunction and interactions with brain injury after cardiac arrest.Resuscitation plus · 2024Review
- Article
- Urine output is an early and strong predictor of acute kidney injury and associated mortality: a systematic literature review of 50 clinical studies.Annals of intensive care · 2024Review
- Post Cardiac Arrest Care in the Cardiac Intensive Care Unit.Current cardiology reports · 2024Review
- Impact of Postarrest Vasoactive-Inotropic Score on Acute Kidney Injury in Cardiac Arrest Survivors: A Retrospective Cohort Study.Reviews in cardiovascular medicine · 2024Article
- High incidence of acute kidney injury in extracorporeal resuscitation, Leading to poor prognosis.Heliyon · 2023Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe aim of this study was to evaluate the incidence and determinants of AKI in a large cohort of cardiac arrest patients.
methodsWe reviewed all patients admitted, for at least 48 hours, to our Dept. of Intensive Care after CA between January 2008 and October 2012. AKI was defined as oligo-anuria (daily urine output <0.5 ml/kg/h) and/or an increase in serum creatinine (≥0.3 mg/dl from admission value within 48 hours or a 1.5 time from baseline level). Demographics, comorbidities, CA details, and ICU interventions were recorded. Neurological outcome was assessed at 3 months using the Cerebral Performance Category scale (CPC 1-2 = favorable outcome; 3-5 = poor outcome).
resultsA total of 199 patients were included, 85 (43%) of whom developed AKI during the ICU stay. Independent predictors of AKI development were older age, chronic renal disease, higher dose of epinephrine, in-hospital CA, presence of shock during the ICU stay, a low creatinine clearance (CrCl) on admission and a high cumulative fluid balance at 48 hours. Patients with AKI had higher hospital mortality (55/85 vs. 57/114, p = 0.04), but AKI was not an independent predictor of poor 3-month neurological outcome.
conclusionsAKI occurred in more than 40% of patients after CA. These patients had more severe hemodynamic impairment and needed more aggressive ICU therapy; however the development of AKI did not influence neurological recovery.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.